A Short Review on Minimum Description Length: An Application to Dimension Reduction in PCA

Bruni, Vittoria; Cardinali, Maria Lucia; Vitulano, Domenico

doi:10.3390/e24020269

Cited by 44 publications

(21 citation statements)

References 67 publications

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“…The variables were selected avoiding the redundancy of those that were in perfect correlation or with high collinearity. Subsequently, an analysis was carried out with the PCA statistical method, which allows the simplification through dimension reduction [ 25 ] of the complexity of sample spaces with many dimensions or variables. This model seeks to maximize the variance extracted by the new variables (components).…”

Section: Methodsmentioning

confidence: 99%

Characterization of Communes with Quality Accredited Primary Healthcare Centers in Chile

Coss-Mandiola

López

Rojas

et al. 2022

IJERPH

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The accreditation process of primary healthcare centers in Chile has not had the same progress as in hospitals, which show high levels of compliance. The purpose of this research is to characterize the communes that have accredited family healthcare centers (CESFAMs) through socio-economic, municipal management, clinical management, and population variables by performing a principal components analysis (PCA) with biplot analysis and a grouping of communes through a hierarchical analysis. The biplot analysis and hierarchical analysis yielded the formation of three large groups of communes with accredited CESFAMs, characterized mainly by population size, number of people registered in the municipal health system, socioeconomic indicators, and financial management and clinical management variables. It was found that the communes that have accredited CESFAMs are characterized by dissimilar behavior in relation to the variables analyzed. Through the model used, it was possible to establish at least three groups of communes according to their behavior against these variables. Of these, the variables of a municipal financial nature were not decisive in achieving the accreditation of the CESFAMs of these communes. Therefore, it is possible that there are other variables or factors that could be facilitating the achievement of accreditation processes.

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Section: Methodsmentioning

confidence: 99%

Characterization of Communes with Quality Accredited Primary Healthcare Centers in Chile

Coss-Mandiola

López

Rojas

et al. 2022

IJERPH

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“…Multivariate statistical analysis PCA is a widely used complex technique to reduce the dimension of multivariate problems. It reduces the dimension of the original data set by resolving correlations between a large number of variables with a smaller number of potential factors, with minimal information loss [31]. We performed a preliminary analysis of the MS datasets using PCA and viewed grouping trends of different processed products.…”

Section: 31mentioning

confidence: 99%

Identification and quality evaluation of different processed products of Aconitum carmichaelii by ultra‐high‐performance liquid chromatography‐quadrupole time‐of‐flight tandem mass spectrometry and ultra‐high‐performance liquid chromatography‐tandem mass spectrometry

Wei

Song

et al. 2023

J of Separation Science

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Aconitum carmichaelii is widely used to treat chronic and intractable diseases due to its remarkable curative effect, but it is also a highly toxic herb with severe cardiac and neurotoxicity. It has been combined with honey for thousands of years to reduce toxicity and enhance efficacy, but there has been no study on the chemical constituent changes in the honey-processing so far. In this study, the chemical constituents of A. carmichaelii before and after honey-processing were characterized by ultra-high-performance liquid chromatography-quadrupole time-of-flight tandem mass spectrometry. The results showed that a total of 118 compounds were identified, of which six compounds disappeared and five compounds were newly produced after honey-processing, and the cleavage pathway of main components was elucidated. At the same time, 25 compounds were found to have significant effects on different products, among which four compounds with the biggest difference were selected for quantitative analysis by ultra-high-performance liquid chromatography-tandem mass spectrometry.This study not only explained the chemical differences between the different products, but also helped to control the quality of the honey-processed products more effectively, and laid a foundation for further elucidating the mechanism of chemical constituent change during the honey-processing of A. carmichaelii.

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“…Principal component analysis (PCA) consisted of expressing a collection of variables in a set of linear combinations of factors not correlated with each other [12,38]. This method allowed the original data (individuals and variables) to be represented in a space with a dimension less than the original space [12,38].…”

Section: Procedures For Quantitative Study Specimens By Principal Com...mentioning

confidence: 99%

A new crotamine-like from the rattlesnake (Crotalus durissus cumanensis) venom causing damages: Qualitative and Quantitative Cytotoxic Studies on subcellular and neuromuscular structures

et al. 2022

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A quantitative model to expose the adrenal gland sub-cellular alterations produced by crotamine-like (C-L) from rattlesnake venom during 3, 6 and 24 hours (h), and also qualitative changes on mice neuromuscular structures in vivo were observed and calculated by transmission electron microscopy. A pure crotamine-like (C-L) isoform was obtained using a cationic exchange chromatography column from the rattlesnake Crotalus durissus cumanensis venom. The C-L SDS-PAGE (15.5 %) under non-reduced conditions exhibited a molecular mass of ~3 kDa single band. The C-L in vivo qualitative experiments induced ultrastructural changes in mouse neuromuscular structures at 3, 6 and 24 h, such as reduction in the number of acetylcholine vesicles, disorganisation of the secondary synaptic clefts, enlargement of the sub-sarcolemma space and alteration of the mitochondria morphology, number and cristae. Regarding neurotoxic actions in vivo, the animals injected with C-L presented spastic paralysis of the hind limbs. The quantitative alterations studied on the capillaries, the nucleus, the mitochondria the lipid inclusions, and the smooth endoplasmic reticulum were observed from 3 to 24 h after C-L injection. As far as it is known from the literature review, there are no quantitative records of similar sub-cellular alterations caused by crotamine.

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A Short Review on Minimum Description Length: An Application to Dimension Reduction in PCA

Cited by 44 publications

References 67 publications

Characterization of Communes with Quality Accredited Primary Healthcare Centers in Chile

Characterization of Communes with Quality Accredited Primary Healthcare Centers in Chile

Identification and quality evaluation of different processed products of Aconitum carmichaelii by ultra‐high‐performance liquid chromatography‐quadrupole time‐of‐flight tandem mass spectrometry and ultra‐high‐performance liquid chromatography‐tandem mass spectrometry

A new crotamine-like from the rattlesnake (Crotalus durissus cumanensis) venom causing damages: Qualitative and Quantitative Cytotoxic Studies on subcellular and neuromuscular structures

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