2019
DOI: 10.15586/jptcp.v26i4.634
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A Shortened Treatment With Rosemary Tea (Rosmarinus Officinalis) Instead of Powder Decreases Insulin Resistance and Serum Glucose in Patients With Diabetes Mellitus Type 2 (T2d)

Abstract: Background Rosemary leaves powder has been reported to reduce in a dose-dependent manner, glucose levels, lipid profile and lipid peroxidation in humans. However, patients should ingest high doses of powder contained in capsules. This formulation constitutes the intake of 10 capsules per day, so the active metabolite must first, be released and then absorbed (for which, rosemary leaf powder must be mixed with gastric juice).

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Cited by 12 publications
(7 citation statements)
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“…Due to its excellent hypoglycemic and hypolipidemic effects, rosemary has been broadly served as a functional ingredient in novel healthy foods, nutraceuticals, and dietary supplements for diabetic patients (El‐Beeh et al., 2019). Especially, rosemary extracts have shown promising potential in the development of antidiabetic drugs (Quirarte‐Baez et al., 2019; Yun et al., 2021). The antidiabetic effects of rosemary include the inhibition of advanced glycation end products (AGEs) produced by glycosylation (Shen et al., 2020), suppression of glycogenesis (Bao et al., 2020), promotion of insulin synthesis and glucose uptake (Lipina & Hundal, 2014; Naimi et al., 2015), enhancement of fat consumption (Razavi et al., 2020), anti‐inflammatory (Bao et al., 2020), antioxidant (Abdelrahman et al., 2020; Selmi et al., 2017), lowering blood lipids (El‐Beeh et al., 2019; Hassani et al., 2016), as well as anti‐atherosclerosis (Rodrigues et al., 2020).…”
Section: Biological Activities Of Rosemary Extractmentioning
confidence: 99%
“…Due to its excellent hypoglycemic and hypolipidemic effects, rosemary has been broadly served as a functional ingredient in novel healthy foods, nutraceuticals, and dietary supplements for diabetic patients (El‐Beeh et al., 2019). Especially, rosemary extracts have shown promising potential in the development of antidiabetic drugs (Quirarte‐Baez et al., 2019; Yun et al., 2021). The antidiabetic effects of rosemary include the inhibition of advanced glycation end products (AGEs) produced by glycosylation (Shen et al., 2020), suppression of glycogenesis (Bao et al., 2020), promotion of insulin synthesis and glucose uptake (Lipina & Hundal, 2014; Naimi et al., 2015), enhancement of fat consumption (Razavi et al., 2020), anti‐inflammatory (Bao et al., 2020), antioxidant (Abdelrahman et al., 2020; Selmi et al., 2017), lowering blood lipids (El‐Beeh et al., 2019; Hassani et al., 2016), as well as anti‐atherosclerosis (Rodrigues et al., 2020).…”
Section: Biological Activities Of Rosemary Extractmentioning
confidence: 99%
“…Finally, the levels of lipid peroxide differed significantly. [12] Diabetic rats were given ginger orally for six weeks. Ginger reduced blood glucose levels, and the liver index was close to normal, as was metformin.…”
Section: Reduction Of Blood Glucose Level By Spices Compoundsmentioning
confidence: 99%
“…Lastly, the anti-inflammatory activity of R. officinalis was characterized by decreased levels of inflammatory biomarkers: COX2, prostaglandin E2, IL-1b, matrix metallopeptidase (MMP2), and nitric oxide (NO) when tested on carbon tetrachloride (CCI4)-induced rats [ 65 ]. In humans, a clinical study carried out on 40 adults (mean age 56 years) diagnosed with T2DM, the intake of rosemary tea (2 g/L of water per day) for 90 days was assessed in order to evaluate whether using rosemary tea instead of powder might have a similar therapeutic effect in the treatment of T2DM, since a large number of leaf powder capsules are required (10 capsules daily) [ 106 ]. The results indicate a decrease in mass index, waist-hip ratio, lipid peroxidation, insulin resistance, and the pancreatic β-cell function ( Table 3 ).…”
Section: Lamiaceae: Bioactive Propertiesmentioning
confidence: 99%