A SiC microdevice for the minimally invasive monitoring of ischemia in living tissues

Fundamentals of Biomedical Applications of Biomorphic SiC

“…the Cole model; Cole, 1940) that can provide additional information through the analysis of derived parameters and improve the reproducibility of results (Raicu et al, 2000). Gomez et al (Gomez et al, 2006) examined the feasibility of producing SiC-based needleshaped impedance probes for continuous monitoring of impedance and temperature in living tissues. SiC needle-shaped impedance probes (see Fig.…”

“…2B) were produced in standard clean room conditions. (Gomez et al, 2006) In-vitro results obtained with SiC based impedance probes were compared with those obtained with Si-based probes, and they demonstrated that the use of SiC substrates was mandatory to extend the effective operation range of impedance probes beyond the 1 kHz range. In-vivo evaluation of SiC-based impedance probes was conducted on rat kidneys undergoing warm ischemia by dissecting and clamping of the renal pedicles.…”

Silicon Carbide: A Biocompatible Semiconductor Used in Advanced Biosensors and BioMEMS/NEMS

“…the Cole model) that can provide additional information through the analysis of derived parameters and improve the reproducibility of results [5]. Gomez et al [38] examined the feasibility of producing SiC-based needle-shaped impedance probes for continuous monitoring of impedance and temperature in living tissues. SiC needle-shaped impedance probes (Fig.6) were produced in standard clean room conditions.…”

“…Figure 6. A) Needle-shaped Si probe for impedance; (B) Needle-shaped SiC probe for impedance; (C) Needle-shaped with packaging [38] In vitro results obtained with SiC based impedance probes were compared with those obtained with Si-based probes, and they demonstrated that the use of SiC substrates was mandatory to extend the effective operation range of impedance probes beyond the 1 kHz range. In-vivo evaluation of SiC-based impedance probes was conducted on rat kidneys undergoing warm ischemia by dissecting and clamping the renal pedicles.…”

Recent improvements of SiC micro‐resonators

“…Silicon Carbide (SiC) appears to be the ideal candidate to depose it for manufacturing microelectromechanical systems due to its superior electrical, mechanical and electrical properties [1]. In the sensors field, UV detectors, impedance needles gas sensors have been already carried out showing superior performances to Si equivalent device [2,3]. In addition, the superior mechanical properties of SiC compared to Si (young modulus and yield strength three times superior) make it appropriate to develop MEMS devices with better characteristics [4][5][6][7].…”