A signal-off photoelectrochemical aptasensor for highly sensitive detection of T-2 toxin using 3D CdS/CdIn2S4 heterostructured nanostars by in-situ generated electron donor strategy

Detection of food contaminants: A review of established rapid analytical techniques and their applications and limitations

“…(e) Schematic representation of the PEC aptasensor for the detection of T‐2 toxin. Recreated with permission from (Wang, Wei, et al., 2023), Copyright 2023, Elsevier. (f) Schematic representation of the NIR‐responsive photocurrent‐polarity‐switchable PEC immunoassay for E. coli O157:H7.…”

“…The combination of biorecognition elements and one or more signal amplification strategies in one sensor system play a crucial part in improving detection sensitivity (Zhao & Ding, 2019). To date, various signal amplification strategies, including Biocatalytic precipitation (BCP) (He, Ying, et al., 2021), He, Ying, et al., 2021onsumption/generation of electron donors/acceptors (Wang, Wei, et al., 2023), and photocurrent polarity switching (Jiang, Zhang, et al., 2022) have been generally applied to detect food contaminants.…”

“…Lin et al., developed a competitive‐type nonenzymatic PEC immunoassay to sensitively detect AFB1, in which the introduced dopamine‐loaded liposome on the MBs could be hydrolyzed by Triton X‐100 to release dopamine, improving the photocurrent (Lin et al., 2017). Wang et al., employed 3D CdS/CdIn 2 S 4 heterostructured nanostars as the photoactive interface to establish a PEC aptasensor for detecting T‐2 toxin with the assistance of ALP‐enzymatic signal amplification method (Figure 4e), further amplify the photocurrent signal by in situ generating ascorbic acid (Wang, Wei, et al., 2023).…”

Photoelectrochemical immunoassay of alpha-fetoprotein based on a SnO2/In2S3 heterojunction and an enzyme-catalyzed precipitation strategy

“…18 To date, steric hindrance effects, energy transfer principles, p–n semiconductor quenching effects and enzymatic reactions have been widely used to output and amplify PEC signals. 19,20 The catalyzed precipitation (CP) reaction can be used to quench the photocurrent signal by generating insoluble precipitates with a steric hindrance effect on the electrode surface and thus give obvious response signals and high sensitivity. 21 CP based on natural enzymes such as horseradish peroxidase (HRP) and alkaline phosphate (ALP) has been reported.…”

“…21 CP based on natural enzymes such as horseradish peroxidase (HRP) and alkaline phosphate (ALP) has been reported. 19,22 On the other hand, nanozymes (nanomaterials with enzyme-like properties) have also been widely used because of their good stability and low cost. CeO 2 has received extensive attention in the fields of photocatalysis and biosensor due to its favorable electrical, optical and peroxidase-like properties.…”