1987
DOI: 10.1016/0014-5793(87)80437-4
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A significant increase of lysophosphatidylinositol 4‐phosphate with insulin in isolated rat fat cells

Abstract: We studied the effects of insulin on the incorporation of 32P i into phospholipids in rat fat cells. When the cells were treated with insulin, a new radioactive phospholipid was detected on thin layer chromatography. The substance migrated slower than phosphatidylinositol 4,5-bisphosphate and was hardly detectable in the absence of insulin. This effect of insulin was both time-and dose-dependent with half-maximal stimulation at 120 #U/ml. Pretreatment of insulin with anti-insulin antibody or the cells with ant… Show more

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Cited by 5 publications
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