A simple and economical chemical neutralization method for the destruction of sulfur mustard and its analogues

Gupta, Arvind; Dubey, D. K.; Kaushik, M. P.

doi:10.1016/j.jhazmat.2006.06.016

Cited by 13 publications

(6 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Section: Resultsmentioning

confidence: 99%

“…It is critical for the oxidation of sulfur mustards to be selective for the sulfoxide without overoxidation to the sulfone as the sulfone derivatives are nearly as toxic as the parent compounds. 26 Three controls were performed for the sulfoxidation reaction. First, the reaction was performed in the absence of catalyst.…”

Section: Resultsmentioning

confidence: 99%

“…The excellent conversion for the oxidation of (chloromethyl)(methyl)sulfide is of particular importance as this sulfide is a model compound for sulfur mustard, which is a highly toxic chemical warfare agent. It is critical for the oxidation of sulfur mustards to be selective for the sulfoxide without overoxidation to the sulfone as the sulfone derivatives are nearly as toxic as the parent compounds …”

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

Mild, Selective Sulfoxidation with Molybdenum(VI) cis-Dioxo Catalysts

2017

View full text Add to dashboard Cite

Three molybdenum(VI) cis -dioxo catalysts ( 8 – 10 ) were synthesized with the goal of developing stable and selective oxidation catalysts for sulfoxidation. Their reactivities were investigated with a variety of substrates. We have demonstrated the usefulness of these catalysts for the chemoselective sulfoxidation of sulfides in the presence of reactive moieties, which has important applications for total synthesis processes. Notably, these catalysts are able to oxidize compounds analogous to sulfur mustard and can be used as an alternative to sodium periodate or meta -chloroperoxybenzoic acid ( m -CPBA) for the oxidation of various organic sulfides without sacrificing total conversion. As the catalysts are tolerant of water and hydrogen peroxide, they allow for the design of completely green oxidation reactions, particularly for sulfur-containing amino acids.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Mild, Selective Sulfoxidation with Molybdenum(VI) cis-Dioxo Catalysts

2017

View full text Add to dashboard Cite

show abstract

“…Mustards 7a – d and 8 were prepared following the methods reported by Gupta and Kaushik with modifications.…”

Section: Methodsmentioning

confidence: 99%

Unexpected Reaction Pathways Leading to Thiodiglycol During the Degradation of Long-Chain Sulfur Mustards

Caballero¹,

Martínez‐Álvarez

Sierra

2018

J. Org. Chem.

View full text Add to dashboard Cite

Degradation of long-chain sulfur mustards with various commercial decontaminants unexpectedly forms thiodiglycol (TDG) through unreported reaction pathways. Chemical warfare agents (CWAs) degradation products have to be unambiguously related to their reference compounds in order to fulfill international verification protocols. Thus, the formation of TDG using water-based decontaminants introduces an uncertainty in the origin of this chemical that has been systematically used to unambiguously demonstrate the presence of yperite in environmental and biomedical samples. Therefore, these novel and unprecedented degradation pathways will result either in modifications of the international verification protocols for forensic purposes or in the exclusion of TDG as an exclusive marker of yperite.

show abstract

“…Owing to the presence of oxidizable bivalent sulfur, the oxidation of HD using organic chloramines is a promising method of decontamination. − Oxidation reactions render the compound harmless to biological systems. Various agents − have been used for decontamination of HD including hypochlorite, , sodium, enzyme-based micro emulsion, , zeolites, iodobenzoic acid complex, nanosize calcium oxide, titania nanotubes, peroxides, and alumina-supported fluoride reagents . We previously reported the use of N,N- dichlorourethane, for the decontamination of O,S- diethyl methylphosphonothiolate , (OSDEMP), a simulant of VX.…”

Section: Introductionmentioning

confidence: 99%

N, N-Dichlorourethane: An Efficient Decontaminating Reagent for Sulfur Mustard, a Chemical Warfare Agent

Singh

Gutch

Mazumder

2013

Ind. Eng. Chem. Res.

View full text Add to dashboard Cite

An efficient and operationally simple method for chemical decontamination of sulfur mustard (HD) has been reported herein. A chlorine-bearing reagent N,N-dichlorourethane was developed to deactivate HD in aqueous (acetonitrile/water, 80/20) medium. This decontamination reaction was monitored by gas chromatography–mass spectrometry and NMR spectroscopy. This reagent is highly efficient, stable, economical, and easy to synthesize and leads to instant decontamination of HD. The reaction was found to instantaneously and completely convert HD to innocent products at different temperatures (−20 to 40 °C).

show abstract

A simple and economical chemical neutralization method for the destruction of sulfur mustard and its analogues

Cited by 13 publications

References 11 publications

Mild, Selective Sulfoxidation with Molybdenum(VI) cis-Dioxo Catalysts

Mild, Selective Sulfoxidation with Molybdenum(VI) cis-Dioxo Catalysts

Unexpected Reaction Pathways Leading to Thiodiglycol During the Degradation of Long-Chain Sulfur Mustards

N, N-Dichlorourethane: An Efficient Decontaminating Reagent for Sulfur Mustard, a Chemical Warfare Agent

Contact Info

Product

Resources

About