A Simple and Efficient Ligand-Free Copper-Catalyzed C-N Bond Formation of Aryl (Hetero) Halides and N-Heteroaryl Amines

Green synthesis of shape-tunable CuFe2O4NPs: a magnetically retrievable and efficient catalyst for Chan–Lam type C–N coupling reactions under base-free conditions

“…Due to the huge importance of bioactive molecules containing C-N bonds in the pharmaceutical industry, efforts toward the improvement in C-N bond-forming reactions always get huge appreciation. 1 Among different reports, Kommuri and his co-workers reported the ligand-free C-N bond formation reaction between aryl (hetero) halides and N-hetero aryl amines by using CuI as the catalyst, DMSO as the solvent, and NaOH as the base with a maximum yield of 81% at 90 1C for 8.0 h. 2 Li et al reported the aza-Michael addition reaction of acryl amides with primary and secondary amines using magnetic Fe 3 O 4 nanoparticles (NPs) as the catalyst and CH 2 Cl 2 as the solvent at room temperature. 3 They obtained a maximum yield of 93.2% and the catalyst was reused for up to 10 cycles with a small loss of the catalytic activity.…”

Three Polyoxometalate-Based Ag–Organic Compounds as Heterogeneous Catalysts for the Synthesis of Benzimidazoles

“…4 PMo was synthesized by a method similar to that for Ag 3 PMo, except the reaction temperature was 170 °C.Red block crystals were formed with a 38% yield based on Mo. Anal.…”