A simple and green method for direct determination of hydrogen peroxide and hypochlorite in household disinfectants based on personal glucose meter

Zhang, Hao; Gong, Zhaomiao; Li, Yan; Yang, Feng‐Qing

doi:10.1016/j.enzmictec.2022.109996

Cited by 7 publications

(2 citation statements)

References 28 publications

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“…For example, a portable and user-friendly PGM-based method was developed (by us) to detect hydrogen peroxide using ascorbate oxidase, and the PGM readout triggered by the ascorbic acid achieved a detection quantification of 2.5 μM for hydrogen peroxide [ 30 ]. Zhang et al developed an easy and green PGM method to detect quantification of hydrogen peroxide and hypochlorite in household disinfectants on the basis of the acetylthiocholine iodide-mediated reaction with the quantification limit of 1.7 mM and 0.9 mM, respectively [ 31 ]. As a common mediator in many glucose test strips, potassium ferricyanide (K 3 [Fe(CN) 6 ]) is an important element for this conversion, which facilitates the electron transfer between the enzymatic reaction and the electrodes to generate the PGM detectable signal.…”

Section: Introductionmentioning

confidence: 99%

A Catechol-Meter Based on Conventional Personal Glucose Meter for Portable Detection of Tyrosinase and Sodium Benzoate

et al. 2022

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In this study, the personal glucose meter (PGM) was first used as a fast and user-friendly meter for analyzing catechol (CA) based on the reduction of the mediator K3[Fe(CN)6] to K4[Fe(CN)6] in the glucose test strip. Then, an easy, low-cost, and convenient PGM-based method for detecting tyrosinase (TYR) activity and sodium benzoate (SBA) was developed on the basis of the TYR-catalyzed reaction. In this method, CA is oxidized to form o-benzoquinone by TYR, thereby reducing the residual amount of CA and the PGM readout. On the other hand, SBA can inhibit the oxidation of CA catalyzed by TYR and increase the residual amount of CA after the enzymatic reaction. Therefore, the activity of TYR is proportional to the difference in the PGM readout of CA, and the concentration of SBA is positively correlated with the residual amount of CA. After the relevant experimental conditions were systematically optimized, the proposed PGM-based method for the detection of TYR and SBA was successfully validated. The liner ranges are 1.0–103.3 U/mL and 6.25–1000 ppm, and the quantification limits are 1.0 U/mL and 6.25 ppm for TYR and SBA, respectively. Moreover, the spiked recovery tests in normal human serum and carbonate beverages (i.e., Cola, Sprite, and Fanta) were performed, and the recoveries (91.6–106.8%) further confirm the applicability of the PGM-based method in real sample analysis.

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Section: Introductionmentioning

confidence: 99%

A Catechol-Meter Based on Conventional Personal Glucose Meter for Portable Detection of Tyrosinase and Sodium Benzoate

et al. 2022

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“…Moreover, many methods based on the PGM for measuring analytes other than glucose have been reported, including DNA [23], enzyme activity and their inhibitors [24][25][26], and heavy metals [27]. For example, a green PGM method was developed for direct determination of hydrogen peroxide and hypochlorite by us [28]. In the method, acetylcholinesterase catalyses the hydrolysis of acetylthiocholine iodide (ATCI) to generate thiocholine iodide, which triggers the reduction of K 3 [Fe(CN) 6 ] to K 4 [Fe(CN) 6 ] in the glucose test strips and generates a PGM detectable signal.…”

Section: Introductionmentioning

confidence: 99%

A Simple and Portable Personal Glucose Meter Method Combined with Molecular Docking for Screening of Lipase Inhibitors

Zhang

Yang

Gao

2022

Evidence-Based Complementary and Alternative Medicine

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With the increase of obesity incidence, the development of antiobesity drugs has aroused extensive interest. In this study, a simple and portable personal glucose meter (PGM) method based on the lipase-mediated reaction combined with molecular docking was developed for the screening of lipase inhibitors. Lipase can catalyse the hydrolysis of 4-acetamidophenyl acetate to form acetaminophen, which can directly trigger the reduction of K3[Fe(CN)6] to K4[Fe(CN)6] in the glucose test strips and generate an electrical signal that can be detected by the PGM. When lipase inhibitors exist, the yield of acetaminophen will be reduced and results in a corresponding decrease of the PGM signal. Therefore, the activity of lipase can be measured by the PGM. After optimization of the experimental conditions, the inhibitory activity of fourteen small-molecule compounds and fifteen natural product extracts on lipase were evaluated by the developed PGM method. The results indicate that tannic acid, (-)-epigallocatechin gallate, (-)-epigallocatechin, (-)-epicatechin gallate, and epicatechin have good inhibitory effect on lipase (% of inhibition higher than 40.0%). Besides, the natural product extracts of Galla Chinensis, lemon, and Rhei Radix et Rhizoma have a good inhibitory effect on lipase with % of inhibition of (97.5 ± 0.6)%, (88.1 ± 0.7)%, and (79.1 ± 1.6)%, respectively. Finally, the binding sites and modes of six small-molecule compounds on lipase were investigated by the molecular docking study. The results show that the developed PGM method is an effective approach for the discovery of potential lipase inhibitors.

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Preparation of Self‐Driven Triboelectric Nanosensor Based on Chitosan‐Coated Ti Foil for Detecting Blood Glucose Concentration

Yao,

Xu,

Zhang

et al. 2024

Adv Eng Mater

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The clinical diagnosis of diabetes mellitus typically depends on blood glucose measurements. Many laboratory studies have focused on enzyme–electrode biosensors that require an external power source. In this study, the potential of triboelectric nanogenerators (TENGs) as self‐driven sensors for glucose detection is investigated by utilizing the glucose specificity of glucose oxidase. When immersed in glucose solutions with concentrations ranging from 3.9 to 13.1 mmol L−1, the TENGs exhibit a linear relationship between the glucose concentration and current and voltage changes. These findings suggest that the TENGs developed in this study can effectively function as glucose sensors, providing a foundation for future human blood glucose monitoring applications and demonstrating a promising new approach for biomedical sensor technology.

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A simple and green method for direct determination of hydrogen peroxide and hypochlorite in household disinfectants based on personal glucose meter

Cited by 7 publications

References 28 publications

A Catechol-Meter Based on Conventional Personal Glucose Meter for Portable Detection of Tyrosinase and Sodium Benzoate

A Catechol-Meter Based on Conventional Personal Glucose Meter for Portable Detection of Tyrosinase and Sodium Benzoate

A Simple and Portable Personal Glucose Meter Method Combined with Molecular Docking for Screening of Lipase Inhibitors

Preparation of Self‐Driven Triboelectric Nanosensor Based on Chitosan‐Coated Ti Foil for Detecting Blood Glucose Concentration

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