A Simple and Highly Stable Porous Gold‐based Electrochemical Sensor for Bisphenol A Detection

Wannapob, Rodtichoti; Thavarungkul, Panote; Dawan, Supaporn; Numnuam, Apon; Limbut, Warakorn; Kanatharana, Proespichaya

doi:10.1002/elan.201600371

Cited by 19 publications

(11 citation statements)

References 48 publications

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“…Another important parameter that was carefully optimized was the distance between the bottom of the microneedle arrays structure and the beaker's bottom. The highly porous gold surface was produced when this gap was not greater than 3 mm, probably because a larger distance would not facilitate the diffusion processes of H + , AuCl4, and Cl − ions towards and away from the electrode surface to enable the aggregation and deposition of the gold atoms on the electrode surface to form the porous structure [44]. In order to demonstrate the improvements in the electrodeposition method in terms of electroactive area, the gold film was characterized electrochemically in 0.5 M H2SO4 at a scan rate of 100 mV s −1 .…”

Section: Sem and Electrochemical Characterization Of H-pg/au Microneementioning

confidence: 99%

Minimally Invasive Glucose Monitoring Using a Highly Porous Gold Microneedles-Based Biosensor: Characterization and Application in Artificial Interstitial Fluid

et al. 2019

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In this paper, we present the first highly porous gold (h-PG) microneedles-based second-generation biosensor for minimally invasive monitoring of glucose in artificial interstitial fluid (ISF). A highly porous microneedles-based electrode was prepared by a simple electrochemical self-templating method that involves two steps, gold electrodeposition and hydrogen bubbling at the electrode, which were realized by applying a potential of −2 V versus a saturated calomel electrode (SCE). The highly porous gold surface of the microneedles was modified by immobilization of 6-(ferrocenyl)hexanethiol (FcSH) as a redox mediator and subsequently by immobilization of a flavin adenine dinucleotide glucose dehydrogenase (FAD-GDH) enzyme using a drop-casting method. The microneedles-based FcSH/FAD-GDH biosensor allows for the detection of glucose in artificial interstitial fluid with an extended linear range (0.1–10 mM), high sensitivity (50.86 µA cm−2 mM−1), stability (20% signal loss after 30 days), selectivity (only ascorbic acid showed a response about 10% of glucose signal), and a short response time (3 s). These properties were favourably compared to other microneedles-based glucose biosensors reported in the literature. Finally, the microneedle-arrays-based second-generation biosensor for glucose detection was tested in artificial interstitial fluid opportunely spiked with different concentrations of glucose (simulating healthy physiological conditions while fasting and after lunch) and by placing the electrode into a simulated chitosan/agarose hydrogel skin model embedded in the artificial ISF (continuous glucose monitoring). The obtained current signals had a lag-time of about 2 min compared to the experiments in solution, but they fit perfectly into the linearity range of the biosensor (0.1–10 mM). These promising results show that the proposed h-PG microneedles-based sensor could be used as a wearable, disposable, user-friendly, and automated diagnostic tool for diabetes patients.

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Section: Sem and Electrochemical Characterization Of H-pg/au Microneementioning

confidence: 99%

Minimally Invasive Glucose Monitoring Using a Highly Porous Gold Microneedles-Based Biosensor: Characterization and Application in Artificial Interstitial Fluid

et al. 2019

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“…A stock solution of BPA obtained from Sigma Aldrich with purity of > 99 % (10.0 mmol L À1 ) was prepared in absolute ethanol and stored at 4 8C. Graphite powder (average particle size < 20 micron), sulphuric acid (H 2 PO 4 ), N,N-dimethylformamide (DMF) with analytical grade were brought from Sigma-Aldrich Chemical Co. The Britton-Robinson (BR) buffer solution prepared at certain pH ranges was used as a supporting electrolyte in electrochemical measurements.…”

Section: Reagents and Solutionsmentioning

confidence: 99%

“…The leaching of BPA from these products is very important for human health since BPA is known as an endocrine disruptor [1,2]. and can be present in the water bottles, plastic food container, infant feeding bottles and etc.…”

Section: Introductionmentioning

confidence: 99%

“…and can be present in the water bottles, plastic food container, infant feeding bottles and etc. The leaching of BPA from these products is very important for human health since BPA is known as an endocrine disruptor [1,2]. It can also cause many problems such as decreasing of sperm quality, increasing of cancer risk by weakening the immune system, diabetes, thyroid disorder etc.…”

Section: Introductionmentioning

confidence: 99%

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Sensitive Voltammetric Determination of Bisphenol A Based on a Glassy Carbon Electrode Modified with Copper Oxide‐Zinc Oxide Decorated on Graphene Oxide

Karabiberoğlu

2018

Electroanalysis

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A highly sensitive and selective chemical sensor was prepared based on metallic copper‐copper oxides and zinc oxide decorated graphene oxide modified glassy carbon electrode (Cu−Zn/GO/GCE) through an easily electrochemical method for the quantification of bisphenol A (BPA). The composite electrode was characterized via scanning electron microscopy (SEM), X‐Ray photoelectron spectroscopy (XPS) and electrochemical impedance spectroscopy (EIS). The electrochemical behavior of BPA in Britton‐Robinson (BR) buffer solution (pH 7.1) was examined using cyclic voltammetry (CV). Under optimized conditions, the square wave voltammetry (SWV) response of Cu−Zn/GO/GCE towards BPA indicates two linear relationships within concentrations (3.0 nmol L−1−0.1 μmol L−1 and 0.35 μmol L−1−20.0 μmol L−) and has a low detection limit (0.88 nmol L−1). The proposed electrochemical sensor based on Cu−Zn/GO/GCE is both time and cost effective, has good reproducibility, high selectivity as well as stability for BPA determination. The developed composite electrode was used to detect BPA in various samples including baby feeding bottle, pacifier, water bottle and food storage container and satisfactory results were obtained with high recoveries.

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“…To monitor the environmental levels, behaviors and fate of BPA, many methods, such as capillary electrophoresis [ 11 ], gas chromatography coupled with mass spectrometry (GC-MS) [ 12 ], high performance liquid chromatography mass spectrometry (HPLC-MS) [ 13 ], enzyme linked immune sorbent assay (ELISA) [ 14 ], electrochemical methods [ 15 , 16 ], etc., have been developed. Combined with pretreatment procedures of solid-phase extraction [ 17 ], liquid-liquid extraction [ 18 ] and immunoaffinity chromatography [ 19 ], GC-MS, HPLC-MS and ELISA can be used for selectively and sensitively determining BPA in complex matrices [ 20 , 21 ].…”

Section: Introductionmentioning

confidence: 99%

In Situ Determination of Bisphenol A in Beverage Using a Molybdenum Selenide/Reduced Graphene Oxide Nanoparticle Composite Modified Glassy Carbon Electrode

Shi

Liang

Zhao

et al. 2018

Sensors

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Due to the endocrine disturbing effects of bisphenol A (BPA) on organisms, rapid detection has become one of the most important techniques for monitoring its levels in the aqueous solutions associated with plastics and human beings. In this paper, a glassy carbon electrode (GCE) modified with molybdenum selenide/reduced graphene oxide (MoSe2/rGO) was fabricated for in situ determination of bisphenol A in several beverages. The surface area of the electrode dramatically increases due to the existence of ultra-thin nanosheets in a flower-like structure of MoSe2. Adding phosphotungstic acid in the electrolyte can significantly enhance the repeatability (RSD = 0.4%) and reproducibility (RSD = 2.2%) of the electrode. Under the optimized condition (pH = 6.5), the linear range of BPA was from 0.1 μM–100 μM and the detection limit was 0.015 μM (S/N = 3). When using the as-prepared electrode for analyzing BPA in beverage samples without any pretreatments, the recoveries ranged from 98–107%, and the concentrations were from below the detection limit to 1.7 μM, indicating its potential prospect for routine analysis of BPA.

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A Simple and Highly Stable Porous Gold‐based Electrochemical Sensor for Bisphenol A Detection

Cited by 19 publications

References 48 publications

Minimally Invasive Glucose Monitoring Using a Highly Porous Gold Microneedles-Based Biosensor: Characterization and Application in Artificial Interstitial Fluid

Minimally Invasive Glucose Monitoring Using a Highly Porous Gold Microneedles-Based Biosensor: Characterization and Application in Artificial Interstitial Fluid

Sensitive Voltammetric Determination of Bisphenol A Based on a Glassy Carbon Electrode Modified with Copper Oxide‐Zinc Oxide Decorated on Graphene Oxide

In Situ Determination of Bisphenol A in Beverage Using a Molybdenum Selenide/Reduced Graphene Oxide Nanoparticle Composite Modified Glassy Carbon Electrode

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