2022
DOI: 10.1039/d2ra03690h
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A simple electrochemical aptasensor for saxitoxin detection

Abstract: The combination between the electrochemical sensor and selective specificity of MB modified aptamer(MB-Apt) yielded an electrochemical aptasensor with a high sensitivity and excellent specific recognition ability to STX.

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Cited by 9 publications
(2 citation statements)
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“…Furthermore, an amperometric sensor based on the aptamer of STX was developed by Zheng et al, as depicted in Figure 8. In the presence of STX, the methylene blue (MB)-tagged aptamer (MB-Apt) specifically binds to the STX and forms a folded conformation, which brings MB closer to the surface of the electrode and facilitates the transfer of electrons to its surface, which leads to an increase in oxidation current [50]. In electrochemical biosensors, the effective modification of biomaterials directly affects the stability of the sensor, and the study of stable nanomaterials and electrodes is one of the ways to solve these problems.…”
Section: Electrochemical Biosensorsmentioning
confidence: 99%
“…Furthermore, an amperometric sensor based on the aptamer of STX was developed by Zheng et al, as depicted in Figure 8. In the presence of STX, the methylene blue (MB)-tagged aptamer (MB-Apt) specifically binds to the STX and forms a folded conformation, which brings MB closer to the surface of the electrode and facilitates the transfer of electrons to its surface, which leads to an increase in oxidation current [50]. In electrochemical biosensors, the effective modification of biomaterials directly affects the stability of the sensor, and the study of stable nanomaterials and electrodes is one of the ways to solve these problems.…”
Section: Electrochemical Biosensorsmentioning
confidence: 99%
“…The receptors and antibodies used in RBA and ELISA are easily affected by the environment and have poor stability, requiring strict storage conditions. In addition, the colorimetric method, [14][15][16][17] fluorescence method, 18,19 and electrochemical detection method [20][21][22][23][24] are also used to detect the toxins of the clam. The measurable range and stability of the colorimetric method are better than those of other rapid detection methods, but the sensitivity is limited.…”
Section: Introductionmentioning
confidence: 99%