A simple exercise test in borderline and sustained essential hypertension

Chaix, Rémi; Dimitriu, V; Wagniart, P; Safar, Michel E.

doi:10.1016/0167-5273(82)90062-6

Cited by 18 publications

(4 citation statements)

References 18 publications

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“…In published studies the sensitivity for prediction of future resting hypertension can be as high as 100% with specificity of between 53 and 95% [22,[28][29][30], Similarly, exercise has been successfully used to investigate the mechanisms of essential hyperten sion [31,32], There are two possible explanations for our findings. Firstly, it could be argued that the degree of renal dys function seen in the CS-treated patients caused the great er systemic vascular resistance.…”

Section: Discussionmentioning

confidence: 48%

“…The use of exercise both to uncover 'latent' hyperten sion and to predict the future development of hyperten sion at rest, is not new [26][27][28]. In published studies the sensitivity for prediction of future resting hypertension can be as high as 100% with specificity of between 53 and 95% [22,[28][29][30], Similarly, exercise has been successfully used to investigate the mechanisms of essential hyperten sion [31,32], There are two possible explanations for our findings.…”

Section: Discussionmentioning

confidence: 81%

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Hypertensive Exercise Responses in Ciclosporin-Treated Normotensive Renal Transplant Recipients

Scott¹,

Hay²,

Higenbottam³

et al. 1990

Nephron

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Although many patients taking ciclosporin (CS) for the long term develop hypertensive side effects, a proportion do not. We have studied the blood pressure response to graded upright bicycle exercise while continuously recording the metabolic rate in 18 normotensive renal transplant recipients whose mean age was 30.8 years (range 16–54). Nine were treated with CS alone and 9 with azathioprine and a steroid, prednisolone (AzS). Both groups performed a progressive exercise test, with work increasing by 25 W every 4 min from rest. All patients completed a workload of at least 75 W during the test. A group of 8 normal subjects whose mean age was 29 years (range 19–44) were exercised with the same protocol. The CS group had a significantly higher mean systemic blood pressure at both 50 and 75 W (124 and 132 mm Hg, respectively), compared with the AzS group (103 and 108 mm Hg; p < 0.01). The blood pressure response to exercise in the AzS group was similar to that observed in the normal group. This was despite a higher metabolic rate at each stage of work in the AzS group as compared with the CS or normal groups. Despite being normotensive at rest, renal transplant patients who are treated with CS have evidence of a vasopressor effect, with systemic vascular resistance inappropriately high for exercise, implying reduced compliance of the vascular bed.

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Section: Discussionmentioning

confidence: 48%

Section: Discussionmentioning

confidence: 81%

Hypertensive Exercise Responses in Ciclosporin-Treated Normotensive Renal Transplant Recipients

Scott¹,

Hay²,

Higenbottam³

et al. 1990

Nephron

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show abstract

“…Age, sex, education, body weight, alcohol consumption, physical fitness, and medication have all been shown to affect the blood pressure response to exercise independently and significantly.18,22 In addition, there was no standardization of the exercise testing protocols employed. Some authors18,20 have used protocols adapting the work load to the heart rate, while others12" 14,16,19 have increased the work load in a predetermined sequence. A third source of ambiguity was the different definitions of "hypertensive response."…”

Section: Resultsmentioning

confidence: 99%

Blood Pressure Response to Exercise as a Predictor of Hypertension

J¹,

Froom²

1986

Arch Intern Med

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“…9 Clearly, using a small sample of age-and sex-matched 'normal' volunteers may give rise to sampling bias. By regrouping 'normal' control subjects, Chaix and colleagues 25 created two control groups with significantly different invasively measured TPR, despite equivalent resting BP readings. For these reasons, we believe that a populationbased definition of normality, as was adopted in the present study is appropriate.…”

Section: Discussionmentioning

confidence: 99%

Dundee step test: a simple method of measuring the blood pressure response to exercise

et al. 1999

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The exercise systolic blood pressure (BP) response provides prognostic information over and above that of resting clinic BP in both normotensive and hypertensive individuals. We have developed a 3-min step test as a method of measuring the exercise systolic BP. Healthy volunteers and patients referred for assessment of hypertension took part in validating this exercise test. We assessed the reproducibility of the exercise systolic BP response, and this was compared with that obtained using the cycle ergometry at an equivalent workload. We also compared the baseline characteristics, BP profiles and exercise systolic BP responses in different subject groups. The intra-observer coefficient of variation assessed in 25 subjects was 5.9% with a mean difference of 1.8 mm Hg. The values for between observer were 8.3% and 2.5 mm Hg respectively. Exercise sys-

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A simple exercise test in borderline and sustained essential hypertension

Cited by 18 publications

References 18 publications

Hypertensive Exercise Responses in Ciclosporin-Treated Normotensive Renal Transplant Recipients

Hypertensive Exercise Responses in Ciclosporin-Treated Normotensive Renal Transplant Recipients

Blood Pressure Response to Exercise as a Predictor of Hypertension

Dundee step test: a simple method of measuring the blood pressure response to exercise

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