A simple method to predict impaired right ventricular performance and disease severity in chronic pulmonary hypertension using strain rate imaging

Utsunomiya, Hiroto; Nakatani, Satoshi; Okada, Takenori; Kanzaki, Hideaki; Kyotani, Shingo; Nakanishi, Norifumi; Kihara, Yasuki; Kitakaze, Masafumi

doi:10.1016/j.ijcard.2009.08.009

Cited by 38 publications

(30 citation statements)

References 33 publications

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“…In addition, according to Utsunomyia et al RV strain has been shown to help analyze the RV function in patients with chronic pulmonary hypertension (20). Similar to our study, it proves the usefulness of RV strain for the assessment of RV, but, unlike our study, it is limited to the patients with chronic pulmonary hypertension.…”

Section: Discussionsupporting

confidence: 87%

Echocardiographic Test and the Early Detection of Systolic Failure in Systemic Sclerosis Patients: Strain and Strain Rate Echocardiography

et al. 2016

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Section: Discussionsupporting

confidence: 87%

Echocardiographic Test and the Early Detection of Systolic Failure in Systemic Sclerosis Patients: Strain and Strain Rate Echocardiography

et al. 2016

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“…Longitudinal systolic strain measurement is also especially well suited to assess RV function because RV contractility predominantly occurs in the longitudinal plane due to the principal orientation of myocardial fibers. 33 Previous studies have demonstrated feasibility for measuring RV strain using speckle-tracking echocardiography in PH 34,35 and other causes of RV dysfunction. [36][37][38][39] However, these studies included limited numbers of patients with PH.…”

Section: Discussionmentioning

confidence: 99%

Outcome Prediction by Quantitative Right Ventricular Function Assessment in 575 Subjects Evaluated for Pulmonary Hypertension

Fine

Chen

Bastiansen

et al. 2013

Circ: Cardiovascular Imaging

380

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Background-Although right ventricular (RV) dysfunction is a major determinant of outcome in patients with pulmonary hypertension (PH), the optimal measure of RV function is poorly defined. We hypothesized that RV strain measured by speckle-tracking echocardiography predicts outcome in PH over a broad range of pulmonary pressures. Methods and Results-Prospective peak RV longitudinal systolic strain measurement was performed on 575 patients (mean age, 56±18 years; 63% women) referred for echocardiography for known or suspected PH. Survival status was assessed over a median of 16.5 (interquartile range, 7.6-20.0) months. There were 406 patients with PH (71%) (74% group 1, 14% group 3, and 12% group 4) and 169 patients without evidence of PH (29%). Among patients with PH, 46% were World Health Organization functional class III-IV. The mean RV strain was −21.2±6.7% for all patients. RV strain declined with worse functional class, shorter 6-minute walk distances, higher N-terminal pro-B-type natriuretic peptide levels, and the presence of right heart failure. RV strain predicted outcome across pulmonary pressures and groups of PH. Eighteenmonth survival was 92%, 88%, 85%, and 71% according to RV strain quartile (P<0.001), with a 1.46 higher risk of death (95% confidence interval, 1.05-2.12) per 6.7% decline in RV strain. RV strain predicted survival when adjusted for pulmonary pressure, pulmonary vascular resistance, and right atrial pressure and provided incremental prognostic value over conventional clinical and echocardiographic variables. Conclusions-Quantitative

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“…Inclusion of interventricular septal strain as a component of global RV strain varies among prior studies. [44][45][46][47] Despite the limitations, previous studies have shown that 2D speckle-tracking strain permits the accurate assessment of RV function in many conditions, especially pulmonary hypertension. 46,47 Although strain is considered relatively load independent, systolic strain is largely an ejection phase index, which is substantially dependent on preload and afterload.…”

Section: Limitationsmentioning

confidence: 99%

Assessment of Ventricular Function in Adults with Sickle Cell Disease: Role of Two-Dimensional Speckle-Tracking Strain

Barbosa

Vasconcelos

Ferrari

et al. 2014

Journal of the American Society of Echocardiography

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A simple method to predict impaired right ventricular performance and disease severity in chronic pulmonary hypertension using strain rate imaging

Cited by 38 publications

References 33 publications

Echocardiographic Test and the Early Detection of Systolic Failure in Systemic Sclerosis Patients: Strain and Strain Rate Echocardiography

Echocardiographic Test and the Early Detection of Systolic Failure in Systemic Sclerosis Patients: Strain and Strain Rate Echocardiography

Outcome Prediction by Quantitative Right Ventricular Function Assessment in 575 Subjects Evaluated for Pulmonary Hypertension

Assessment of Ventricular Function in Adults with Sickle Cell Disease: Role of Two-Dimensional Speckle-Tracking Strain

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