A simple paper-based aptasensor for ultrasensitive detection of lead (II) ion

Khoshbin, Zahra; Housaindokht, Mohammad Reza; Izadyar, Mohammad; Verdian, Asma; Bozorgmehr, Mohammad Reza

doi:10.1016/j.aca.2019.04.049

Cited by 68 publications

(26 citation statements)

References 79 publications

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“…Aptamers are obtained from the random oligonucleotide libraries through the systematic evolution of ligands by the exponential enrichment (SELEX) process including the repetitive processes of binding, selection, and amplification of oligonucleotides (Bai et al, 2017; Bostan et al, 2017; M. Jafari et al, 2018; Khoshbin, Housaindokht, Izadyar, Verdian, et al, 2019; S.‐E. Wang & Si, 2013).…”

Section: Introductionmentioning

confidence: 99%

Recent advances in computational methods for biosensor design

Khoshbin

Housaindokht

Izadyar

et al. 2020

Biotech & Bioengineering

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Biosensors are analytical tools with a great application in healthcare, food quality control, and environmental monitoring. They are of considerable interest to be designed by using cost‐effective and efficient approaches. Designing biosensors with improved functionality or application in new target detection has been converted to a fast‐growing field of biomedicine and biotechnology branches. Experimental efforts have led to valuable successes in the field of biosensor design; however, some deficiencies restrict their utilization for this purpose. Computational design of biosensors is introduced as a promising key to eliminate the gap. A set of reliable structure prediction of the biosensor segments, their stability, and accurate descriptors of molecular interactions are required to computationally design biosensors. In this review, we provide a comprehensive insight into the progress of computational methods to guide the design and development of biosensors, including molecular dynamics simulation, quantum mechanics calculations, molecular docking, virtual screening, and a combination of them as the hybrid methodologies. By relying on the recent advances in the computational methods, an opportunity emerged for them to be complementary or an alternative to the experimental methods in the field of biosensor design.

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Section: Introductionmentioning

confidence: 99%

Recent advances in computational methods for biosensor design

Khoshbin

Housaindokht

Izadyar

et al. 2020

Biotech & Bioengineering

Self Cite

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“…Similarly, in the EC and SERS methods, the detection performance can be improved by patterning nanomaterials with good electrical conductivity on the electrode surface [120,125,135,166,167]. In CL and fluorescence methods, the intensity of the detection signal can be amplified through the catalytic reaction of nanomaterials and the induced fluorescence quenching [132,[168][169][170], respectively. Many studies have confirmed that the detection performance of microfluidic lab-on-paper platforms can be improved through the use of sample pre-concentration techniques (such as ICP, ITP, EKS, and so on) [72,73,75,115,171], or amplification devices (e.g., LAMP, PCR, CHR, HCR, and so forth.)…”

Section: Discussionmentioning

confidence: 99%

Lab-on-Paper Devices for Diagnosis of Human Diseases Using Urine Samples—A Review

et al. 2021

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In recent years, microfluidic lab-on-paper devices have emerged as a rapid and low-cost alternative to traditional laboratory tests. Additionally, they were widely considered as a promising solution for point-of-care testing (POCT) at home or regions that lack medical infrastructure and resources. This review describes important advances in microfluidic lab-on-paper diagnostics for human health monitoring and disease diagnosis over the past five years. The review commenced by explaining the choice of paper, fabrication methods, and detection techniques to realize microfluidic lab-on-paper devices. Then, the sample pretreatment procedure used to improve the detection performance of lab-on-paper devices was introduced. Furthermore, an in-depth review of lab-on-paper devices for disease measurement based on an analysis of urine samples was presented. The review concludes with the potential challenges that the future development of commercial microfluidic lab-on-paper platforms for human disease detection would face.

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“…[ 44–49 ] A paper‐based sensor with a size as low as 2 mm was manufactured by Khoshbin and co‐workers using the drop‐casting method, which only required a small volume of functional materials and analyte (1 μL each) for quantitative analysis. [ 50 ]…”

Section: Preparation Of Paper‐based Sensorsmentioning

confidence: 99%

“…In situ generation is a composite scheme of directly synthesizing functional materials on paper through incubation, [ 50,55 ] hydrothermal reaction, [ 56 ] catalytic reaction, [ 57 ] and photocatalysis reaction [ 58 ] after loading a catalyst or precursor on a paper substrate. This technique may improve the uniformity of function material distribution and effectively ameliorate the ‘coffee ring effect’ caused by the shape and flow direction of the particles in the fluid.…”

Section: Preparation Of Paper‐based Sensorsmentioning

confidence: 99%

Recent advances of environmental pollutants detection via paper‐based sensing strategy

Zou

et al. 2021

Luminescence

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Paper has become one of the most promising substrates for building low‐cost and powerful sensing platforms due to its self‐pumping ability and compatibility with multiple patterning methods. Paper‐based sensors have been greatly developed in the field of environmental monitoring. In this review, we introduced the research and application of paper‐based sensors in environmental monitoring, focusing on the deposition and patterning methods of building paper‐based sensors, and summarized the applications of detecting environmental pollutants, including metal ions, anions, explosives, neurotoxins, volatile organic compounds, and small molecules. In addition, the development prospects and challenges of promoting paper‐based sensors are also discussed. The current review will provide references for the construction of portable paper‐based sensors, and has implications for the field of on‐site real‐time detection of the environment.

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A simple paper-based aptasensor for ultrasensitive detection of lead (II) ion

Cited by 68 publications

References 79 publications

Recent advances in computational methods for biosensor design

Recent advances in computational methods for biosensor design

Lab-on-Paper Devices for Diagnosis of Human Diseases Using Urine Samples—A Review

Recent advances of environmental pollutants detection via paper‐based sensing strategy

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