The seismic excitation experienced by structures is a function of the earthquake source, travel path effects, local site effects, and soil-structure interaction (SSI) influences. The result of the first three of these factors is referred to as ''free-field'' ground motion. Structural response to free-field motion is influenced by SSI. In particular, accelerations within structures are affected by the flexibility of foundation support and variations between foundation and free-field motions. Consequently, an accurate assessment of inertial forces and displacements in structures can require a rational treatment of soil-structure interaction effects. In the present study, in order to depict these effects on seismic response of moment resisting building frames, a ten storey moment resisting building frame resting on a shallow foundation is selected in conjunction with three soil types with shear wave velocities less that 600m/s, representing soil classes building frames increase relatively. In brief, the conventional elastic and inelastic design procedure excluding SSI is not adequate to guarantee the structural safety for moment resisting building frames resting on soil classes D e and E e .