A Single-Center Experience of 260 Consecutive Patients Undergoing Capsule Endoscopy for Obscure Gastrointestinal Bleeding

Carey, Elizabeth J.; Leighton, Jonathan A.; Heigh, Russell I.; Shiff, Arthur D.; Sharma, Virender K.; Post, Janice; Fleischer, David E.

doi:10.1111/j.1572-0241.2006.00941.x

Cited by 281 publications

(223 citation statements)

References 22 publications

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“…The procedure also requires less physician training than advanced endoscopic techniques. The main disadvantages are the inability to manoeuvre the capsule, the lack of therapeutic capabilities, and the relative contraindication of possible strictures, because of the risk of impaction [7,8]. Furthermore, although most images are excellent, they are still not comparable to the view achieved at conventional endoscopy with gas insufflation.…”

Section: Small-bowel Capsule Endoscopymentioning

confidence: 93%

Role of small-bowel endoscopy in the management of patients with inflammatory bowel disease: an international OMED–ECCO consensus

Bourreille¹,

Ignjatovic²,

Aabakken³

et al. 2009

Endoscopy

304

185

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Section: Small-bowel Capsule Endoscopymentioning

confidence: 93%

Role of small-bowel endoscopy in the management of patients with inflammatory bowel disease: an international OMED–ECCO consensus

Bourreille¹,

Ignjatovic²,

Aabakken³

et al. 2009

Endoscopy

304

185

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“…During an 8-h inspection, problems of missed diagnosis and ileus are possible [3]. To improve the situation, active CE equipment with a self-actuation mechanism, which is called capsule robot, is currently under development in several laboratories [4][5][6][7][8][9].…”

Section: Introductionmentioning

confidence: 99%

Modeling of Velocity-dependent Frictional Resistance of a Capsule Robot Inside an Intestine

et al. 2012

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A model is first built for predicting the velocity-dependent frictional resistance of a capsule robot that moves inside the intestine in the paper. The capsule robot plays a more and more important role in checking diseases in the intestine. This study aims to optimize the locomotion mechanism and the control strategy of the capsule robot. The model consists of three parts: environmental resistance, viscous friction, and Coulomb friction. Environmental resistance is induced by the stress due to the viscoelastic deformation of the intestinal wall. Viscous friction is analyzed according to the apparent viscosity of intestinal mucus. Coulomb friction is a product of the local contact pressure and the Coulomb friction coefficient. In order to analyze the effects of the intestinal deformation, a five-element model is used to describe the stress relaxation of the intestinal material. Experimental investigation is used to identify the model parameters with homemade physical simulation measurement system and fixtures. Finally, the model's validity is verified by experimental results. It is shown that the model predicting results can fit the experimental results well when the moving velocity of the capsule is lower than 20 mm/s. The R 2 of these two sets of data is 0.8769. But at a higher velocity, there are significant differences between the two results and the R 2 declines to 0.1666. The friction model is expected to be useful in the development of the medical equipment in the intestine and the study of biomechanics of the intestine.

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“…Additional data supported that patients with positive VCE require longer hospitalization as well as higher number of blood units transfused than those with negative VCE exams (19,21,25,50,55). Even on the occasion of a rebleeding episode, patients with negative index VCE require neither hospital admission nor blood transfusions (25).…”

Section: Impact On Subsequent Therapeutic Strategies and Clinical Outmentioning

confidence: 61%

“…In a trial of 260 patients, outcomes appeared to improve after VCE: patients experienced fewer bleeding events and interventions per month following VCE than those they did pre-VCE (50). However, these results are limited by the variable interval of patient follow-up preand post-VCE, as in any retrospective study.…”

Section: Impact On Subsequent Therapeutic Strategies and Clinical Outmentioning

confidence: 74%

Long-term effects of video capsule endoscopy in the management of obscure gastrointestinal bleeding

et al. 2017

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Obscure gastrointestinal bleeding (OGIB) accounts for approximately 5% of all gastrointestinal (GI) hemorrhages. It usually arises from a small bowel lesion beyond the reach of conventional endoscopy including esophagogastroduodenoscopy and colonoscopy. Video capsule endoscopy (VCE) revolutionized the evaluation of OGIB patients since it allows reliable and noninvasive visualization of the small bowel mucosal surface. Since 2001, VCE has evolved into an efficient technology integrated in clinical practice. It is the cornerstone in the algorithm of OGIB investigation given its high diagnostic yield, which compares favorably to that of double-balloon enteroscopy (DBE). In terms of outcomes, a positive index VCE examination usually correlates to a high re-bleeding rate, while a negative one provides adequate evidence of low re-bleeding risk, suggesting a wait and watch approach in this subset of patients. Additionally, a variety of factors has been acknowledged as significant predictors of re-bleeding episodes. While research data regarding immediate endoscopic findings have matured, data concerning the clinical utility of VCE in patients with OGIB on the long-term remain sparse. This manuscript reviews the current literature, aiming to highlight the role of VCE in the long-term management of OGIB.

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A Single-Center Experience of 260 Consecutive Patients Undergoing Capsule Endoscopy for Obscure Gastrointestinal Bleeding

Cited by 281 publications

References 22 publications

Role of small-bowel endoscopy in the management of patients with inflammatory bowel disease: an international OMED–ECCO consensus

Role of small-bowel endoscopy in the management of patients with inflammatory bowel disease: an international OMED–ECCO consensus

Modeling of Velocity-dependent Frictional Resistance of a Capsule Robot Inside an Intestine

Long-term effects of video capsule endoscopy in the management of obscure gastrointestinal bleeding

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