To support various fifth generation (5G) wireless applications, a small, printed bowtie-shaped microstrip antenna with meandered arms is reported in this article. Because it spans the broad legal range, the developed antenna can serve or reject a variety of applications such as wireless fidelity (Wi-Fi), sub-6 GHz, and ultra-wideband (UWB) 5G communications due to its multiband characterization and optimized rejection bands. The antenna is built on an FR-4 substrate and powered via a 50-Ω microstrip feed line linked to the right bowtie’s side. The bowtie’s left side is coupled via a shorting pin to a partial ground at the antenna’s back side. A gradually increasing meandering microstrip line is connected to both sides of the bowtie to enhance the rejection and operating bands. The designed antenna has seven operating frequency bands of (2.43–3.03) GHz, (3.71–4.23) GHz, (4.76–5.38) GHz, (5.83–6.54) GHz, (6.85–7.44) GHz, (7.56–8.01) GHz, and (9.27–13.88) GHz. The simulated scattering parameter S11 reveals six rejection bands with percentage bandwidths of 33.87%, 15.73%, 11.71, 7.63%, 6.99%, and 12.22%, respectively. The maximum gain of the proposed antenna is 4.46 dB. The suggested antenna has been built, and the simulation and measurement results are very similar. The reported antenna is expanded to a four-element design to investigate its MIMO characteristics.