The Enhanced Model Reference Adaptive Control (EMRAC) algorithm, augmenting the MRAC strategy with adaptive integral and adaptive switching control actions, is an effective solution to impose reference dynamics to plants affected by parameter uncertainties, unmodeled dynamics and disturbances.However, the design of the EMRAC solutions has so far been limited to single-input systems. To cover the gap, this paper presents two extensions of EMRAC to multi-input systems. The adaptive mechanism of both solutions includes the 𝜎-modification strategy to assure the boundedness of the adaptive gains also in presence of persistent disturbances. The closed-loop system is analytically studied, and conditions for the asymptotic convergence of the tracking error are presented. Furthermore, when the plant is subjected to unmatched disturbances, the ultimate boundedness of the closed-loop dynamics, which are made discontinuous by the adaptive switching control actions, is systematically proven by using Lyapunov theory for Filippov systems. The problem of trajectory tracking for space robotic arms in presence of unknown and noncooperative targets is used to test the effectiveness of the novel multi-input EMRAC algorithms for taming uncertain systems. Four EMRAC solutions are designed for this engineering application, and tested within a high fidelity simulation framework based on the Robot Operating System. Finally, the tracking performance of the EMRAC implementations is quantitatively evaluated via a set of key performance indicators in the joint space and operational space, and compared with that of four benchmarking controllers.