A smart chemosensor with different response mechanisms to multi-analytes: Chromogenic and fluorogenic recognition of Cu2+, Fe3+, and Zn2+

Li, Da; Liu, Ailan; Xing, Yifan; Li, Zhijun; Luo, Yuan; Zhao, S. J.; Dong, Li Min; Xie, Tianyou; Guo, Kunpeng; Li, Jie

doi:10.1016/j.dyepig.2023.111180

Cited by 11 publications

(4 citation statements)

References 34 publications

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“…It can disrupt their physiological processes, impair growth and reproduction, and cause mortality. Zinc contamination can also affect the ecosystem balance and biodiversity in aquatic habitats [109]. Monitoring zinc levels can help understand its distribution and regulation within living organisms and its role in health and disease [110].…”

Section: Schiff Bases As Chemosensors For Zn 2+mentioning

confidence: 99%

Strategies for Improving Selectivity and Sensitivity of Schiff Base Fluorescent Chemosensors for Toxic and Heavy Metals

Musikavanhu,

Liang,

Xue

et al. 2023

Molecules

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Toxic cations, including heavy metals, pose significant environmental and health risks, necessitating the development of reliable detection methods. This review investigates the techniques and approaches used to strengthen the sensitivity and selectivity of Schiff base fluorescent chemosensors designed specifically to detect toxic and heavy metal cations. The paper explores a range of strategies, including functional group variations, structural modifications, and the integration of nanomaterials or auxiliary receptors, to amplify the efficiency of these chemosensors. By improving selectivity towards targeted cations and achieving heightened sensitivity and detection limits, consequently, these strategies contribute to the advancement of accurate and efficient detection methods while increasing the range of end-use applications. The findings discussed in this review offer valuable insights into the potential of leveraging Schiff base fluorescent chemosensors for the accurate and reliable detection and monitoring of heavy metal cations in various fields, including environmental monitoring, biomedical research, and industrial safety.

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Section: Schiff Bases As Chemosensors For Zn 2+mentioning

confidence: 99%

Strategies for Improving Selectivity and Sensitivity of Schiff Base Fluorescent Chemosensors for Toxic and Heavy Metals

Musikavanhu,

Liang,

Xue

et al. 2023

Molecules

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“…4,5 In recent years, there is a particular emphasis on the creation of highly selective and sensitive chemosensors for iron ions (Fe 3+ ), with a focus on generating simple absorbance and turn-on fluorescence responses. 6,7 The significance of targeting these specific metal ions lies in their essential roles as vital elements in the human body. Iron, in particular, holds a central position, participating in critical processes such as oxygen metabolism and enzymatic reactions.…”

Section: Introductionmentioning

confidence: 99%

Starch/rhodamine 6G conjugate as a non-cytotoxic, effective, and selective fluorescent chemosensor for detection of Fe³⁺ ion

Alavifar,

Golshan,

Salami Hosseini

et al. 2024

Polymers from Renewable Resources

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Iron is a crucial trace mineral vital for maintaining optimal human health and well-being. Despite being needed in small amounts, its importance cannot be overstated as it plays an important role in various physiological processes. In this research, we have developed a fluorescence probe utilizing starch functionalized with derivatives of rhodamine 6G to efficiently detect Fe3+ ions. This structure forms self-assembled starch/rhodamine 6G (RS0) fluorescent nanoparticles that exhibit strong fluorescence intensity under ultraviolet light. The ability of Fe3+ ions to increase the fluorescence of the RS0 probe enables the effective detection of Fe3+ ions. Importantly, this fluorescence increasing effect is specific to Fe3+ ions and remains unaffected by the presence of other metal ions. MTT assay against SH-SY5Y cells showed that RS0 was rather cytocompatible. Finally, SH-SY5Y cells were used to measure cell uptake and fluorescence imaging performances of RS0 which showed a good ability for live-cell fluorescence imaging.

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“…Among various analytical techniques to detect metal ions in biological and environmental samples [ 29 ], fluorescence spectroscopy possesses many advantages over others in terms of affordability, quick response, convenience, easy operation, on-site detection/monitoring, and naked eye recognition [ 30 , 31 , 32 , 33 , 34 , 35 ]. Thus, many researchers have made efforts to create selective, reliable, convenient, and efficient sensors with a variety of fluorescent platforms, such as fluorescein, rhodamine B, triphenylamine, quinolone, pyrene, anthraquinone, chalcone, benzothiazole/benzimidazole amine, coumarin-conjugated di-(2-picolyl)amine, peptide, and Schiff base compounds [ 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 ]. Many of these probes utilized ethylene diamine-like structures for strong and selective Cu 2+ binding among different metal ions, leading to high selectivity toward Cu 2+ detection.…”

Section: Introductionmentioning

confidence: 99%

“…K. Guo and J. Li used an imine-linked triphenylamine–benzothiazole conjugate as a metal ion-sensing probe. The probe containing an ethylenediamine-like binding site for metal ions was able to detect two metal ions (Cu 2+ and Fe 3+ ) in CH 3 CN, with LODs of 0.3 and 3 μM, respectively [ 37 ]. The probe showed a color change from colorless to red in the presence of Cu 2+ , while the interaction of the probe with Fe 3+ resulted in the ‘switch on’ fluorescence emission.…”

Section: Introductionmentioning

confidence: 99%

A Naphthoquinoline-Dione-Based Cu2+ Sensing Probe with Visible Color Change and Fluorescence Quenching in an Aqueous Organic Solution

Kumar,

Chae

2024

Molecules

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Copper metal ions (Cu2+) are widely used in various industries, and their salts are used as supplementary components in agriculture and medicine. As this metal ion is associated with various health issues, it is necessary to detect and monitor it in environmental and biological samples. In the present report, we synthesized a naphthoquinoline-dione-based probe 1 containing three ester groups to investigate its ability to detect metal ions in an aqueous solution. Among various metal ions, probe 1 showed a vivid color change from yellow to colorless in the presence of Cu2+, as observed by the naked eye. The ratiometric method using the absorbance ratio (A413/A476) resulted in a limit of detection (LOD) of 1 µM for Cu2+. In addition, the intense yellow-green fluorescence was quenched upon the addition of Cu2+, resulting in a calculated LOD of 5 nM. Thus, probe 1 has the potential for dual response toward Cu2+ detection through color change and fluorescence quenching. 1H-NMR investigation and density functional theory (DFT) calculations indicate 1:1 binding of the metal ion to the small cavity of the probe comprising four functional groups: the carbonyl group of the amide (O), the amino group (N), and two t-butyl ester groups (O). When adsorbed onto various solid surfaces, such as cotton, silica, and filter paper, the probe showed effective detection of Cu2+ via fluorescence quenching. Probe 1 was also useful for Cu2+ sensing in environmental samples (sea and drain water) and biological samples (live HeLa cells).

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A smart chemosensor with different response mechanisms to multi-analytes: Chromogenic and fluorogenic recognition of Cu2+, Fe3+, and Zn2+

Cited by 11 publications

References 34 publications

Strategies for Improving Selectivity and Sensitivity of Schiff Base Fluorescent Chemosensors for Toxic and Heavy Metals

Strategies for Improving Selectivity and Sensitivity of Schiff Base Fluorescent Chemosensors for Toxic and Heavy Metals

Starch/rhodamine 6G conjugate as a non-cytotoxic, effective, and selective fluorescent chemosensor for detection of Fe³⁺ ion

A Naphthoquinoline-Dione-Based Cu2+ Sensing Probe with Visible Color Change and Fluorescence Quenching in an Aqueous Organic Solution

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A smart chemosensor with different response mechanisms to multi-analytes: Chromogenic and fluorogenic recognition of Cu2+, Fe3+, and Zn2+

Cited by 11 publications

References 34 publications

Strategies for Improving Selectivity and Sensitivity of Schiff Base Fluorescent Chemosensors for Toxic and Heavy Metals

Strategies for Improving Selectivity and Sensitivity of Schiff Base Fluorescent Chemosensors for Toxic and Heavy Metals

Starch/rhodamine 6G conjugate as a non-cytotoxic, effective, and selective fluorescent chemosensor for detection of Fe3+ ion

A Naphthoquinoline-Dione-Based Cu2+ Sensing Probe with Visible Color Change and Fluorescence Quenching in an Aqueous Organic Solution

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Starch/rhodamine 6G conjugate as a non-cytotoxic, effective, and selective fluorescent chemosensor for detection of Fe³⁺ ion