The article analyzes and evaluates costs, transport time and CO2 emissions by selected vans. The research was carried out on the example of three models of Iveco Daily vehicles powered by: diesel oil, electricity and compressed natural gas (CNG). The result of the research presented in the article is the determination of the operating costs of vehicles powered by various energy sources and the level of CO2 emissions. The comparative analysis was carried out on real data for the established transport task. Vehicles with engines powered by compressed natural gas are characterized by the highest savings in terms of transport costs. As the authors pointed out, this may be due to the fact that this type of engines, despite the low interest of buyers at the moment, may gain much more popularity in the future. On the other hand, in relation to vehicles with electric motors, the cost of transport is the highest, which means that this type of technology is ineffective in relation to long-distance transport.