A So-Called Carcinosarcoma of the Gallbladder in a Patient with Multiple Anomalies. A Case Report.

Surgical management of gallbladder sarcomatoid carcinoma

“…Symptoms may persist from several days to years. Liver function tests are normal, except in patients with obstructive jaundice caused by tumor invasion of the biliar y tract [3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18] . Most cases have been reported to have normal CEA and CA19-9 levels, and in our series, the CEA level was elevated in one case and CA19-9 level was elevated in two cases.…”

“…Chao et al [1] have reported the incidence of sarcomatoid carcinoma from gallbladder cancer as 4.1%. It has been described that sarcomatoid carcinoma arises from totipotent stromal stem cells [8] and is composed of epithelial and mesenchymal components that contain undifferentiated spindle or stellate cells [3,4,6,8,9,11,[14][15][16][17][18] . The cancer was first reported by Landsteiner in 1907, and until now, only 44 cases have been reported in the English-language literature, with an age range of 45-91 years [2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18] .…”

“…The most common histological type of gallbladder cancer is adenocarcinoma, and sarcomatoid carcinoma is extremely rare [2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18] . Chao et al [1] have reported the incidence of sarcomatoid carcinoma from gallbladder cancer as 4.1%.…”

“…Tumors that possess epithelial and mesenchymal components are so-called sarcomatoid carcinomas. Gallbladder sarcomatoid carcinoma is a rare and atypical subset of gallbladder carcinoma, and only 44 cases have been described in the English-language literature worldwide [3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18] . All of these have been case reports and have little information about the clinical behavior and optimal treatment of these tumors.…”

So-Called Carcinosarcoma of the Gallbladder; Spindle Cell Carcinoma of the Gallbladder: Report of a Case

“…2 Carcinosarcomas of the gallbladder are rare, and 28 cases have been described in the English literature [3][4][5][6][7] and 34 cases in the Japanese literature. 8 Sarcomatous metaplasia of a spindle or pleomorphic carcinoma and florid sarcomatous reaction in a Reprint requests to: H. Yamaue Received: June 18, 2001 / Accepted: November 20, 2001 and was either a low malignant entity, or at an early stage of malignancy.…”