A solvent-tuning fluorescence sensor for In(III) and Al(III) ions and its bioimaging application

Charge-Dependent Strategy Enables a Single Fluorescent Probe to Study the Interaction Relationship between Mitochondria and Lipid Droplets

“…In order to in situ observe their relationship in real time, fluorescent probe technology − has been developed. Therefore, a co-staining experiment with two different fluorescent probes is often used for simultaneous imaging and analysis of the mitochondria and LDs. , However, the two different probes have different uptakes, localization, and metabolism profiles, which may lead to failure of fully synchronous detection in the imaging process. , To solve this problem, multifunctional fluorescent probes are gradually developed for simultaneously imaging two or more intracellular substances, including ions, molecules, and organelles. − However, a fluorescent probe for simultaneously staining mitochondria and LDs is rarely reported. − As far as we know, only one work reported by Kralj et al uses 4-amino- N -adamantylphthalimide dye to image the two organelles . Unfortunately, the interaction relationships between mitochondria and LDs have not been studied.…”

Single Fluorescent Probe Separately and Continuously Visualize H2S and HClO in Lysosomes with Different Fluorescence Signals

“…Recently, there have been many outstanding achievements which could respectively or continuously detect two related active small molecules in cells with different signal models. − However, all of these probes could only detect the related active small molecules in the whole cell instead of a specific organelle. More recently, well-designed fluorescent probes which could track the biomolecules of interest in the specific subcellular organelles have been constructed. , However, it is rare to describe a single fluorescent probe which could respectively or continuously detect two related active small molecules within organelles with different fluorescence signals.…”

A simple, azulene-based colorimetric probe for the detection of nitrite in water

“…To evaluate the colorimetric response of 9, sodium nitrite was added to a solution of 9 in acetonitrile-water, acidified with HCl (aq) to pH 1. It is known that choice of solvent can influence both the sensitivity and selectivity of chemical probes [46][47][48] in this instance the final solvent ratio MeCN/H 2 O was 1:1. A range of other conditions having different pH values were also assessed, but it was found that pH 1 was optimum (see ESM for details).…”