A special discovery of pancreatic adenocarcinoma by Sister Mary-Joseph’s Nodule: what is the prognosis?

Abstract

Cutaneous metastases of visceral tumours are uncommon and might have umbilical and/or extra umbilical locations. The umbilical location, also named «Nodule of Sister Mary-Joseph» among 7 to 9% is secondary to a pancreatic tumour. In this article, we reported a case of a 50-years-old man presenting pancreatic cancer discovered by umbilical nodules and weight loss noticed 3 months earlier treated by palliative chemotherapy. We report this case of a rare presentation of cutaneous metastases of pancreatic disease to insist on its bad prognosis level.

Upper gastrointestinal haemorrhage caused by duodenal metastasis from primary lung cancer: A case report

“… 1 These metastases are usually asymptomatic but may be revealed by perforation, obstruction, malabsorption, or bleeding. 2 , 3 Bleeding, as the first presentation of duodenal metastases, is rare and related to poor patient survival. We present a case of a 58‐year‐old patient with upper gastrointestinal bleeding due to duodenal metastases from a primary lung adenocarcinoma.…”

“…They usually occur in patients with terminal‐stage disease 1 . These metastases are usually asymptomatic but may be revealed by perforation, obstruction, malabsorption, or bleeding 2,3 . Bleeding, as the first presentation of duodenal metastases, is rare and related to poor patient survival.…”

Metastatic Pancreatic Adenocarcinoma to Umbilical Skin

“…The metastasis to the umbilical skin is more common than other parts of the skin [ 3 , 4 ]. Sir Hamilton Bailey described SMJN in 1949 and there have been reports of more than 600 cases in the literature mainly from the stomach, ovary and large intestine since then [ 5 ]. Additionally, these nodules may be primarily associated with melanoma, squamous cell carcinoma or sarcoma [ 6 ].…”