2006
DOI: 10.1097/01.ta.0000199392.91772.44
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A Special Report on the Chitosan-based Hemostatic Dressing: Experience in Current Combat Operations

Abstract: This report on the field use of the HemCon dressing by medics suggests that it is a useful hemostatic dressing for prehospital combat casualties and supports further study to confirm efficacy.

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Cited by 528 publications
(356 citation statements)
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“…Responding to feedback from medics and corpsman on the battlefield, a number of products and therapeutic devices have been fielded to the battlefield for hemorrhage control, including new hemostatic dressings and newly tested and selected tourniquets. 26,27 Reports from the battlefield thus far have documented efficacy of both dressings and tourniquets in the tactical environment similar to those in the literature.…”
Section: Battlefield Carementioning
confidence: 79%
“…Responding to feedback from medics and corpsman on the battlefield, a number of products and therapeutic devices have been fielded to the battlefield for hemorrhage control, including new hemostatic dressings and newly tested and selected tourniquets. 26,27 Reports from the battlefield thus far have documented efficacy of both dressings and tourniquets in the tactical environment similar to those in the literature.…”
Section: Battlefield Carementioning
confidence: 79%
“…Chitosan is a widely used biomaterial with an established safety profile in humans. It is used as a pharmaceutical excipient [7], a controversial weight loss supplement [10,11], an experimental mucosal adjuvant [12][13][14] and in an FDA-approved hemostatic dressing [15]. When administered intranasally, chitosan is well-tolerated with only transient mild-to-moderate symptoms mostly of rhinorrhea [12][13][14].…”
Section: Introductionmentioning
confidence: 99%
“…Two injury models [6][7][8][9][10][11][12][13], a full femoral transection (including artery and vein) and a femoral artery puncture yield massive blood loss in the early phase of bleeding and severe hemorrhagic shock consequences if untreated. Our previous results indicated that dressing efficacy outcomes were different across these two injury models [1,2].…”
Section: Introductionmentioning
confidence: 99%