A spectrum of clinical signs in anterior uveitis

Abstract

The range of clinical changes that occur in posterior uvei tis have been well documented. We describe two clinical features of anterior uveitis which we have termed 'iris pigment epithelitis' and 'iris vasculitis'. Other clinical forms of iritis also exist and together with our described findings parallel the spectrum of clinical presentations in posterior uveitis.

Pigment dispersion syndrome and pigmentary glaucoma – a major review

“…Anterior uveitis can cause iris pigment epithelitis with the release of pigment, inflammatory cells and debris into the AC, which can be mistaken for PDS 70 . The loss of pigment epithelial cells is often associated with iris trans‐illumination defects 70 . Herpetic uveitis is a common cause of iris trans‐illumination defects associated with elevated IOP 68 .…”

“…70 The loss of pigment epithelial cells is often associated with iris trans-illumination defects. 70 Herpetic uveitis is a common cause of iris transillumination defects associated with elevated IOP. 68 Furthermore, uveitis can cause patchy increased TM pigmentation.…”

Immunopathogenic Mechanisms in Intraocular Inflammation

“…Cases of sarcoidosis have shown the typical noncaseating granulomas while clinical patterns of ASII vasculitis have been differentiated from pigment epitheliitis on iris fluorescein angiograms [40]. A series of iris biopsies revealed differential expression of various adhesion molecules on iris biopsies from patients with ASII, taken during surgery for the complications of the disease [41].…”

Acute myelogenous leukaemia presenting as a conjunctival lesion and red eye

“…This is an unusual case of secondary glaucoma associated with anterior uveitis, pigment dispersion secondary to presumed iris pigment epithelitis and herpetic eye infection. Herpes simplex uveitis can present as kerato-uveitis, endothelitis, trabeculitis or a combination of these (Dawson & Togni 1976;Dua et al 1993). This case was unusual in several respects.…”