A step closer in reducing hemolysis in blood samples collected in the emergency department

Kavsak, Peter A.

doi:10.1016/j.clinbiochem.2013.04.002

Cited by 7 publications

(5 citation statements)

References 11 publications

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“…Due to the high prevalence of hemolysis in samples received from the ED, several strategies were proposed to overcome the problem ( 3 ). The use of traditional means of collection other than drawing blood from intravenous lines has been widely advocated ( 4 ), but this suggestion has been largely overlooked due to the fact that blood drawing from catheters is thought to save time as well as human and economical resources that are required for both patient care and blood drawing in short stay units.…”

Section: Introductionmentioning

confidence: 99%

The use of S-Monovette is effective to reduce the burden of hemolysis in a large urban emergency department

et al. 2015

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BackgroundDue to the high prevalence of hemolysis in specimens received from the emergency department (ED), several strategies have been proposed to improve sample quality, but none of these seem effective to overcome the problem. In a preliminary study we showed that the use of S-Monovette blood collection system was effective to lower the risk of hemolysis in venous blood samples collected from intravenous catheters. This study was hence aimed to verify whether the replacement of a conventional vacuum system with S-Monovette may be effective to reduce the burden of hemolysis in the daily practice of a large urban ED.Materials and methodsThe study was divided in two observational periods of 4 months each. In the former period, blood was collected from intravenous catheters using BD Vacutainer SST II Plus plastic serum tubes, whereas in the latter period the blood was drawn from intravenous catheters using S-Monovette blood tubes in aspiration mode. Sample hemolysis was automatically assessed in all serum samples by photometrical measurement.ResultsThe total number of hemolysed serum specimens was 624/14155 (4.41%) in the first phase of the study, and 342/13319 (2.57%) in the second phase of the study (P < 0.001).ConclusionResults of our study confirm that the introduction of the Sarstedt S-Monovette blood tubes has reduced the hemolysis rate in the emergency department compared to the previously used BD Vacutainer® SST II Plus plastic serum tubes.

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Section: Introductionmentioning

confidence: 99%

The use of S-Monovette is effective to reduce the burden of hemolysis in a large urban emergency department

et al. 2015

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“…This was higher than the prevalence of haemolysed samples (H-index N5) at 0.6%, which were mainly from ED patients. The increased rate of haemolysed samples arriving from the ED (i.e., via collections through IV catheters) has been well documented and the potential effect that haemolysis has on cardiac troponin interpretation [6,7]. There are mechanisms that can be employed to lessen the amount of haemolysed samples [7]; however, this cannot be done for high bilirubin concentrations/icteric samples.…”

Section: Clinica Chimica Acta J O U R N a L H O M E P A G E : W W W mentioning

confidence: 97%

Matrix and bilirubin interference for high-sensitivity cardiac troponin I

Simons

Beach

Clark

et al. 2015

Clinica Chimica Acta

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“…creatinine kinase, lactate dehydrogenase (LDH), alanine amino transferase (ALT), aspartate amino transferase, (AST), potassium, coagulation tests [3]. Hemolysis in samples is observed regularly in departments that the patients spend relatively short time in, such as the emergency department [4,5].…”

Section: Introductionmentioning

confidence: 99%

The Effectiveness of Using Luer-Lok (Bd Vacutainer®) In Reducing Hemolysis Rates in Busy Emergency Departments

Keşaplı¹,

Güngör²,

Aykal³

et al. 2016

J Nurs Care

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Introduction: In busy emergency departments, errors made during the pre-analytical phase can cause delayed diagnosis and treatment, and prolonged follow-up periods. The most common error in the pre-analytical phase is hemolysis in blood samples. In this study, we aimed to assess the effectiveness of the Luer-Lok (BD Vacutainer ®) method of taking samples in avoiding hemolysis. Materials and Methods: The study was conducted at the emergency department of a tertiary healthcare facility on patients that register at level 1 or 2 of the Emergency Severity Index triage algorithm. Three sets of prospective observations were made, each lasting for five days. In the first period, hemolysis rates were determined. Following a training course on appropriate blood sampling techniques during the second period, hemolysis rates were determined again while Luer-Lok (BD Vacutainer ®) was being used. Taking and processing of samples were carried out by the same personnel throughout the study. Assessment of hemolysis was performed by those that were blind to sampling. All the samples were analyzed at the laboratory located inside the emergency department. Results: In total, 2,027 blood samples were sent to the emergency laboratory for analysis. The hemolysis rate was 8.1% in the first period, 5.5% in the second and 1.4% in the third. The difference in rates between the first and second periods was not statistically significant (p=0.0793). The hemolysis rate in the third period was significantly lower compared to the other two periods (p=0.0001). Conclusion: Using Luer-Lok (BD Vacutainer ®) may be effective in reducing hemolysis rates in busy emergency departments.

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A step closer in reducing hemolysis in blood samples collected in the emergency department

Cited by 7 publications

References 11 publications

The use of S-Monovette is effective to reduce the burden of hemolysis in a large urban emergency department

The use of S-Monovette is effective to reduce the burden of hemolysis in a large urban emergency department

Matrix and bilirubin interference for high-sensitivity cardiac troponin I

The Effectiveness of Using Luer-Lok (Bd Vacutainer®) In Reducing Hemolysis Rates in Busy Emergency Departments

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