High-resolution signal reconstruction from a set of its noisy low-resolution measurements is considered. As an alternative solution to this problem, a method employing the empirical mode decomposition (EMD) based denoising approach is proposed. In the framework of the proposed method, iterative EMD interval-thresholding based denoising procedure is applied to each noisy low-resolution measurement so as to filter the additive white Gaussian noise effect on it. We then synthesize the noise-reduced low-resolution signals to form the high-resolution signal. Unlike the method using the Wiener filter theory for highresolution signal reconstruction, the proposed method does not require knowledge of any correlation information about the desired high-resolution signal and its low-resolution versions. The validity of the proposed method is demonstrated by an audio signal reconstruction application.