A Straightforward Approach to Multifunctional Graphene

Abstract

Graphene has been covalently functionalized throughaone-pot reductive pathway using graphite intercalation compounds (GICs),i np articularK C 8 ,w ith three different orthogonally protected derivatives of 4-aminobenzylamine. This novel multifunctional platform exhibits excellent bulk functionalization homogeneity (H bulk )a nd degree of addition whilepreserving the chemical functionalities of the organic addends throughd ifferent protecting groups, namely: tert-butyloxycarbonyl (Boc), benzyloxycarbonyl (Cbz) and phthalimide (Pht). We have employed( temperature-dependent) statisticalR aman spectroscopy (SRS), X-ray photoelec-tron spectroscopy (XPS), magic angle spinning solid state 13 CNMR (MAS-NMR), and ac haracterizationt ool consisting of thermogravimetric analysisc oupledw ith gas chromatography and mass spectrometry (TG-GC-MS) to unambiguously demonstrate the covalentb inding and the chemical nature of the different molecular linkers. This work paves the way for the development of smart graphene-based materials of great interesti nb iomedicine or electronics, to name af ew, and will serve as ag uide in the designo fn ew 2D multifunctionalm aterials.

Is carboxylation an efficient method for graphene oxide functionalization?

“…The colorimetric Kaiser test was used to determine the amount of amino-PEG groups graed onto GO aer Boc deprotection. 30,49,50 The epoxide ring opening reaction was rst performed since the epoxides easily react with amines through a nucleophilic addition forming C-N bonds and new hydroxyl groups, 29 which can be further derivatized with chloroacetic acid. For this purpose, the pristine GO was mixed with BocNH-PEG 10 -NH 2 in water and stirred for 3 days at room temperature (Scheme 2).…”

Rational Chemical Multifunctionalization of Graphene Interface Enhances Targeted Cancer Therapy

“…The platform designed for our study is characterized by the presence of three functionalities, ICG as the fluorophore, FA as the targeting agent and DOX as the therapeutic molecule. The starting material to prepare this platform corresponds to a multifunctional graphene recently described (Supporting Information, Figure S1) . mfG, obtained through one‐pot covalent multifunctionalization of KC 8 with diazonium salts, is bearing three orthogonally protected benzylamine derivatives that allow a specific strategy of step‐by‐step amine deprotection and functionalization.…”

Infrared spectroscopy quantification of functional carbon groups in kerogens and coals: A calibration procedure

“…All spectra were collected within a 250kHz spectral windows (1325.3ppm) and 16324 acquisition time domains. To get undistorted lineshapes and filter out background probes signal, the quantitative Direct Polarization (DP) was performed using a speed synchronized spin-echo (Hahn, 1950;Vieira et al, 2016;Lucherelli et al, 2019), pulse sequence P90-τ-P180-τ, with the following conditions: 2.75 µs and 5.5º s for P90° and P180° pulses, and echo time being set to 33.6 µs (2 rotation periods). Under such conditions, baseline problems and first order phasing are fixed, which is a prerequisite for quantitative analysis.…”