A straightforward logistic method for feeding a fed-batch baker's yeast culture

Borowiak, Daniel; Miśkiewicz, Tadeusz; Miszczak, Witold; Cibis, Edmund; Krzywonos, Małgorzata

doi:10.1016/j.bej.2011.09.016

Cited by 7 publications

(2 citation statements)

References 19 publications

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“…Significant complexity arises in maintaining the biomass concentration along a desired trajectory while simultaneously holding the ethanol concentration below a certain value. The final biomass or ethanol concentration that is achieved varies with the operating conditions and the control schemes used (Atasoy et al, 2013;Valentinotti et al, 2003;Borowiak et al, 2012;Chuo et al, 2011;Yüzgeç et al, 2009;Hitit et al, 2014).…”

Section: Maximization Of Biomass With High Inoculum Densitymentioning

confidence: 99%

Maximizing biomass concentration in baker’s yeast process by using a decoupled geometric controller for substrate and dissolved oxygen

Chopda

Rathore

Gomes

2015

Bioresource Technology

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Section: Maximization Of Biomass With High Inoculum Densitymentioning

confidence: 99%

Maximizing biomass concentration in baker’s yeast process by using a decoupled geometric controller for substrate and dissolved oxygen

Chopda

Rathore

Gomes

2015

Bioresource Technology

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“…biomass and capacity to enhance yield or productivity by controlled addition of nutrients. The fed-batch fermentations are used in large scale for the production of baker's yeast, pure ethanol (Figure 2) [23].…”

Section: Fed-batch Cultivationmentioning

confidence: 99%

Fermentation: A Potential Strategy for Microbial Metabolite Production

Sheikh,

G. Anand,

B. Shivanna

2024

The Science of Fermentation [Working Title]

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Fermentation is derived from a Latin word fermentum, a process of chemical changes in an organic substrate by the action of microbial enzymes. The science of fermentation is called as zymology, and the first zymologist was Louis Pasteur. Study of fermentation is called as fermentation technology. Fermenter or bioreactor is the heart of fermentation technology where the whole study is involved. It is a container with biomechanical and biochemical environment that controls the transfer of oxygen, nutrient to the cells, and metabolic products from the cells. There are different types of fermenters like stirred tank fermenter, airlift fermenter, bubble column reactor, fluidized-bed reactor, packed bed reactor, and membrane bioreactor. There are different processes such as batch, continuous, and fed batch or semi-continuous. Secondary metabolites are produced either through submerged or solid-state fermentation process during the stationary phase of an organism. These metabolites are showing a rising demand in food, cosmetics, drugs, and other industries. The production of these metabolites can be improved by strain improvement through mutagenesis and r-DNA technologies. This chapter focuses on all these areas in detail.

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A novel strategy and kinetics analysis of half‐fractional high cell density fed‐batch cultivation of Zygosaccharomyces rouxii

Zhou

Yang

et al. 2018

Food Science & Nutrition

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Zygosaccharomyces rouxii is an important microorganism for aroma production in traditional fermented foods. Using Z. rouxii as the original strain, the batch was split after glucose depletion in the culture medium. Half of the volume of the culture medium was released, and fresh culture medium was fed in. The exponential culture kinetics and the formula for the half‐fractional fed‐batch cultivations were determined to achieve a new strategy for high cell density culturing of Z. rouxii. Based on a full cultivation, three half‐fractional fed‐batch cultivations were performed after every 10 hr of culture. The specific growth rates of Z. rouxii at the different stages were in the order μX0>μX1>μX2>μX3 (0.525 to 0.229 hr−1). The glucose substrate consumption rates gradually decreased following the order μS0>μS1>μS2>μS3 (−1.165 to −0.722, g/g). The equation models for cell growth and glucose substrate consumption showed typical exponential behavior. The total cell yield was 1.78‐fold higher than the yield from a full cultivation, and this continuous subculture strategy also indicated a higher efficiency than traditional full cultivation. A new strategy for highly efficient culturing of Z. rouxii was achieved in a pilot scale. A foundation with data support for the production and application of Z. rouxii was developed.

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A straightforward logistic method for feeding a fed-batch baker's yeast culture

Cited by 7 publications

References 19 publications

Maximizing biomass concentration in baker’s yeast process by using a decoupled geometric controller for substrate and dissolved oxygen

Maximizing biomass concentration in baker’s yeast process by using a decoupled geometric controller for substrate and dissolved oxygen

Fermentation: A Potential Strategy for Microbial Metabolite Production

A novel strategy and kinetics analysis of half‐fractional high cell density fed‐batch cultivation of Zygosaccharomyces rouxii

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