We give a characterization of the Hoffman constant of a system of linear constraints in R n relative to a reference polyhedron R ⊆ R n . The reference polyhedron R represents constraints that are easy to satisfy such as box constraints. In the special case R = R n , we obtain a novel characterization of the classical Hoffman constant.More precisely, suppose R ⊆ R n is a reference polyhedron, A ∈ R m×n , and A(R) :Our characterization is stated in terms of the largest of a canonical collection of easily computable Hoffman constants. Our characterization in turn suggests new algorithmic procedures to compute Hoffman constants.Furthermore, observe that if J ∈ S(A) andṽ ∈ ext{v ∈ R J + , A T J v * ≤ 1} then A J ′ must have full row rank for J ′ := {i :ṽ i > 0} ⊆ J. Therefore Proposition 2 also implies thatwhich is precisely the characterization (4) of H(A). In addition, Proposition 2 implies the following bound on H(A) in terms of the χ(A) condition measure [41,44,46] established in [50] for the special case when A ∈ R m×n is full column rank and both R m and R n are endowed with Euclidean norms:|J |=n A J non-singular max{ v : v ∈ R J , A T J v ≤ 1} = max J ⊆[m],|J |=n A J non-singular A −1 J = χ(A). The last step follows from [50, Prop. 3.7].