A Structural Model of Quality of Life in Patients after Colorectal Cancer Surgery

Yeom, Jeong Won; Suh, Yeon Ok

doi:10.3390/ijerph19052564

Cited by 3 publications

(1 citation statement)

References 38 publications

(62 reference statements)

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“…Therefore, recognizing the potential impact of the above factors on patient well-being is crucial in understanding the context in which the study was conducted and the generalizability of the findings to other settings or time periods. According to previous studies, there were models to predict quality-of-life outcomes among patients with pancreatic cancer (28), cervical cancer survivors (29), colorectal cancer survivors (30,31), patients who underwent colorectal cancer surgery (32), and patients who underwent prostate radiation therapy (33)…”

Section: Discussionmentioning

confidence: 99%

Prediction of postoperative health-related quality of life among patients with metastatic spinal cord compression secondary to lung cancer

Fu,

Shi,

Zhao

et al. 2023

Front. Endocrinol.

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BackgroundHealth-related quality of life (HRQoL) is a critical aspect of overall well-being for patients with lung cancer, particularly those with metastatic spinal cord compression (MSCC). However, there is currently a lack of universal evaluation of HRQoL in this specific patient population. The aim of this study was to develop a nomogram that can accurately predict HRQoL outcomes in patients with lung cancer-related MSCC.MethodsA total of 119 patients diagnosed with MSCC secondary to lung cancer were prospectively collected for analysis in the study. The least absolute shrinkage and selection operator (LASSO) regression analysis, along with 10-fold cross-validation, was employed to select the most significant variables for inclusion in the nomogram. Discriminative and calibration abilities were assessed using the concordance index (C-index), discrimination slope, calibration plots, and goodness-of-fit tests. Net reclassification index (NRI) and integrated discrimination improvement (IDI) analyses were conducted to compare the nomogram’s performance with and without the consideration of comorbidities.ResultsFour variables were selected to construct the final nomogram, including the Eastern Cooperative Oncology Group (ECOG) score, targeted therapy, anxiety scale, and number of comorbidities. The C-index was 0.87, with a discrimination slope of 0.47, indicating a favorable discriminative ability. Calibration plots and goodness-of-fit tests revealed a high level of consistency between the predicted and observed probabilities of poor HRQoL. The NRI (0.404, 95% CI: 0.074–0.734, p = 0.016) and the IDI (0.035, 95% CI: 0.004–0.066, p = 0.027) confirmed the superior performance of the nomogram with the consideration of comorbidities.ConclusionsThis study develops a prediction nomogram that can assist clinicians in evaluating postoperative HRQoL in patients with lung cancer-related MSCC. This nomogram provides a valuable tool for risk stratification and personalized treatment planning in this specific patient population.

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Section: Discussionmentioning

confidence: 99%

Prediction of postoperative health-related quality of life among patients with metastatic spinal cord compression secondary to lung cancer

Fu,

Shi,

Zhao

et al. 2023

Front. Endocrinol.

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A causal model of health-related quality of life in colorectal cancer patients post-surgery

Tran,

Thanasilp,

Pudtong

2024

European Journal of Oncology Nursing

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Patient perspective on adapting to bowel dysfunction after rectal cancer surgery

Maalouf,

Wang,

Robitaille

et al. 2024

Colorectal Disease

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AimBowel dysfunction continues to be a clinically significant consequence of rectal cancer surgery, affecting quality of life. Rectal cancer patients value self‐empowerment and adaptation to change to improve their quality of life in the context of bowel dysfunction. There are limited qualitative data addressing patients' perspectives on adapting to bowel dysfunction. The aim of this study is to evaluate patients’ perspectives on adapting to bowel dysfunction after rectal cancer surgery.MethodAdult patients who underwent rectal cancer surgery with sphincter preservation at a single colorectal referral centre from July 2017 to July 2020 were included. Patients were excluded if they had surgery <1 year since recruitment, received a permanent stoma or developed recurrence or metastasis. Semistructured interviews were held by phone and transcribed verbatim. Bowel dysfunction was assessed via the low anterior resection syndrome (LARS) score. Thematic analysis was used to identify adaptations which patients found helpful for improving bowel dysfunction after rectal cancer surgery.ResultsA total of 54 patient interviews were included. The distribution of patients with no, minor and major LARS was 39%, 22% and 39%, respectively. Four main themes were conceived from the analysis: implementing lifestyle changes, fostering supportive relationships and self‐compassion, communication and access to resources, and adapting to social and cultural challenges. Associated subthemes were identified, namely forward planning, self‐compassion and addressing social stigma.ConclusionPatients' valuable perspective on adapting to bowel dysfunction involve subtle themes which expand the existing literature. These themes inform a patient‐centred approach, which may improve outcomes and quality of care for rectal cancer patients.

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A Structural Model of Quality of Life in Patients after Colorectal Cancer Surgery

Cited by 3 publications

References 38 publications

Prediction of postoperative health-related quality of life among patients with metastatic spinal cord compression secondary to lung cancer

Prediction of postoperative health-related quality of life among patients with metastatic spinal cord compression secondary to lung cancer

A causal model of health-related quality of life in colorectal cancer patients post-surgery

Patient perspective on adapting to bowel dysfunction after rectal cancer surgery

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