A study of 31 cases of gastric carcinoma in dogs

Sullivan, Martin; Lee, R; Fisher, EW; Nash, AS; McCandlish, IA

doi:10.1136/vr.120.4.79

Cited by 56 publications

(47 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Other authors showed the incidence of these tumours up to 1% (Swan and Holt 2002) and up to 3% (Russell et al 2007). We found highly significant percentage of all gastric tumours represented by adenocarcinomas (93.8%); higher incidence of malignant epithelial tumours was also confirmed by other authors (Sautter and Hanlon 1975; Patnaik et al 1977;Sullivan et al 1987;Swan and Holt 2002). Some authors found higher incidence of gastric tumours in male dogs (Simpson 2010).…”

Section: Discussionsupporting

confidence: 90%

“…According to most of the studies, it seems that breed and sex do not play a significant role in the frequency of tumour incidence; however, some studies indicated a higher incidence of gastric carcinomas in male elderly dogs compared to females (Patnaik et al 1977;Twedt 1992). Some authors also proved higher incidence of gastric carcinomas in some breeds of dogs such as Rough Collie, Staffordshire Bull Terrier and Belgian Shepherd (Sullivan et al 1987;Fonda et al 1989;Scanziani et al 1991).…”

mentioning

confidence: 94%

See 1 more Smart Citation

Canine gastrointestinal tract tumours: a restrospective study of 74 cases

et al. 2013

View full text Add to dashboard Cite

The aim of our study was to investigate histopathologically the incidence of gastrointestinal tract tumours in dogs in the Czech Republic in relation to their age, sex and breed. In total, 29 gastric and 45 intestinal tumours from 3827 gastrointestinal tract biopsies were investigated. The average age of dogs with gastric lymphoma, adenocarcinoma, and other mesenchymal tumours was 7.3 years, 9.5 years, and > 10 years, respectively. Breed predisposition to adenocarcinoma was evidenced in the Belgian Shepherd and Leonberger, to lymphoma in the Doberman (P < 0.01). The most frequent site of adenocarcinoma was antrum pyloricum (66.7%); lymphomas involved gastric wall diffusely. The average age of dogs with intestinal adenoma, adenocarcinoma, lymphoma, leiomyoma or leiomyosarcoma and carcinoid was 7.5, 8.5, 8.5, 12, and 14 years, respectively. The age predisposition to intestinal adenoma and lymphoma was 7-8 years (P < 0.01) and to adenocarcinoma 7-8 years (P < 0.05); mesenchymal tumours occurred at the age of 11-12 years (P < 0.01). Breed predisposition to intestinal adenoma was evidenced in the Pug, Leonberger and English Setter (P < 0.01), to adenocarcinoma in the English Setter (P < 0.01) and Hovawart (P < 0.05), to lymphoma in the Doberman and Hovawart (P < 0.05). The most frequent site of occurrence of intestinal tumours was the colorectal region. The study revealing breed, sex and age predisposition to gastrointestinal tumours in dogs has not been described yet in the literature.

show abstract

Section: Discussionsupporting

confidence: 90%

mentioning

confidence: 94%

Canine gastrointestinal tract tumours: a restrospective study of 74 cases

et al. 2013

View full text Add to dashboard Cite

show abstract

“…Canine gastric cancer is rarely diagnosed and is reported to account for approximately 0.1–0.5% of canine neoplasias [1-3]. However, it is still more prevalent in dogs than in other domestic animals [4].…”

Section: Introductionmentioning

confidence: 99%

Breed predisposition to canine gastric carcinoma - a study based on the Norwegian canine cancer register

et al. 2013

View full text Add to dashboard Cite

BackgroundPrevious research has indicated a breed predisposition to gastric carcinoma in dogs. However, results to date are inconsistent since several studies have failed to prove such a predisposition. Better knowledge of breeds at risk could facilitate early detection of gastric carcinoma in dogs. The aim of the study was to retrospectively investigate the proportion and possible breed predisposition to canine gastric carcinoma using the Norwegian Canine Cancer Register for calculations of proportional morbidity ratios (PMRs) for the period 1998–2009.ResultsHistologically verified tumours recorded in the Norwegian Canine Cancer Register were studied (n = 19,715). A total of 31 (0.16%) cases of canine gastric carcinomas were identified. The median age of affected dogs was 10 years. The most commonly reported clinical signs were vomiting, anorexia, and weight loss. Males had significantly higher odds of gastric carcinoma than females (P = 0.02). The PMR with 95% confidence interval (CI) was calculated for each breed, and a breed predisposition was identified. Individuals of the breeds Tervuren (PMR 56.1), Bouvier des Flandres (PMR 36.5), Groenendael (PMR 34.5), Collie (PMR 26.1), Standard poodle (PMR 7.6), and Norwegian elkhound (PMR 6.1) had a significantly increased risk of developing gastric carcinoma.Discussion and conclusionThe proportion of cases of gastric carcinoma recorded in the Norwegian Canine Cancer Register was found to be 0.16%, and a breed predisposition was identified. The breed predisposition observed in the current study indicates a genetic susceptibility to gastric carcinoma.

show abstract

“…This type of carcinoma forms tubular structures and exhibit various patterns at different levels of invasion of the stomach wall. Among dogs, gastric carcinoma has been reported to affect males more frequently than females [11]. Gastric carcinoma is a disease of older dogs, but has been reported in dogs in the age range of 3-20 yrs.…”

Section: Treatment and Discussionmentioning

confidence: 99%

A Report of Gastric Adenocarcinoma in a Dog

Shafiuzama

Babu

Krishnaveni

et al. 2015

IJAVST

View full text Add to dashboard Cite

An 11 year old male non-descript dog was presented with the history of frequent vomition and progressive weight loss for the past one month. The dog was dull, dehydrated, anaemic and emasciated. Positive contrast survey radiographs, revealed delayed gastrointestinal transit time and absence of foreign body. Exploratory laparatomy was done which revealed thickening of entire layer of the gastric wall with pylorus and the histopathology revealed gastric adenocarcinoma. Since the tumor was spread to the full thickness of the stomach wall including pylorus, the prognosis was informed to the owner and euthanasia was advised.

show abstract

A study of 31 cases of gastric carcinoma in dogs

Cited by 56 publications

References 0 publications

Canine gastrointestinal tract tumours: a restrospective study of 74 cases

Canine gastrointestinal tract tumours: a restrospective study of 74 cases

Breed predisposition to canine gastric carcinoma - a study based on the Norwegian canine cancer register

A Report of Gastric Adenocarcinoma in a Dog

Contact Info

Product

Resources

About