A study of abnormal cervical cytology in pregnant women

Abstract

During the 4 year routine study of smears in 2,919 pregnant women, 33 cases of abnormals of the uterine cervix were detected (1.13%). The patients were followed with uterine cervical cytology and colposcopy and in case of need, sometimes punch biopsies were performed. The results of the cytologies, 33 cases with abnormalities were detected. There were 26 cases classified as class IIIa, 7 cases were class IIIb. All the cases underwent colposcopy. For the 17 cases that showed lesions by colposcopy, and punch biopsies were performed. The results of histologic examination were wide variety, five chronic cervicitis, one condyloma, one mild dysplasia, three moderate dysplasia, three severe dysplasia, three carcinoma in situ, and one microinvasive carcinoma. Only two cases were treated during pregnancy; one with condyloma underwent Laser vaporization and another with microinvasive carcinoma underwent LEEP conization. Other cases were given conservative treatment during pregnancy. Excluding one case for persistence smear class IIIa of histology condyloma, all the cases showed regression of dysplasia and carcinoma in situ with treatment after delivery. We conclude that lesions up to carcinoma in situ do not require intervention during pregnancy but microinvasive carcinoma is suspected, diagnostic LEEP conization is necessary, even during pregnancy.

Secondary cervical cancer prevention in routine prenatal care — coverage, results and lessons for the future

“…Therefore, routine antenatal Pap smear is such an important examination. Abnormal cervical cytology is observed in about 5% of gravidas [17][18][19]. In our study the percentage was slightly lower than the average -2.3%.…”

Morbility and Mortality for Cervical Cancer in the Isle of Youth, 2003-2015

“…among the infections of sexual transmission -overalls the human viral papilloma [7,8] and the cervical cancer justifies that the growing behavior of the first ones mainly at the end of the second and third decades of life it makes that cases of cancer appear in young ages.…”

Retrospective Evaluation of CO₂ Laser Conization in Pregnant Women with Carcinoma in situ or Microinvasive Carcinoma

“…The annual report of the Gynecologic Cancer Committee of the Japan Society of Obstetrics and Gynecology in 2005 [1] reported that 77.0% of stage 0 and 43.6% of stage Ia1 cervical cancers were treated by conization. Early-stage cervical cancer frequently occurs at a young age, and the frequency of abnormal cervical cytology in pregnant women has increased from 0.8 % [2] to 1.13% [3] over the past 10 years in Japan. We retrospectively examined results of long-term follow-up to evaluate the efficacy and safety of CO 2 laser conization for pregnant women with biopsy-proven cervical intraepithelial neoplasia 3/carcinoma in situ (CIN3/CIS) or microinvasive carcinoma (MIC) of the uterine cervix.…”