A Study of Aesthetic and Functional Outcome Following Structural Fat Grafting for Facial Scars and Contour Deformity

Rao, Anantheswar Y. N.; Reddy, Sudarshan; Chandrappa, Ashok B; Vasudevan, Srikanth; Batth, Rittu

doi:10.1177/1943387520948709

Cited by 4 publications

(4 citation statements)

References 11 publications

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“…The aesthetic outcome as scored on the VAS scale showed a mean score of 8.2, and 6 patients (20%) scored the aesthetic outcome with a VAS score of 10. Such a mean score was superior to that obtained by Rao et al (16) who reported an aesthetic outcome with a mean VAS score of 7.1 (±1.26) using fat grafting to improve aesthetic and functional outcomes in facial scars.…”

Section: Discussioncontrasting

confidence: 75%

Aesthetic Outcomes of Botulinum Toxin Injection for Management of Disfiguring Forehead Scars

Abdelmaksoud,

Rashwan,

Omran

2021

SJMS

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Objectives: The evaluation of the aesthetic outcomes of Botulinum toxin A (BTXA) injection after the excision of disfiguring forehead scars. Patients and Methods: 30 patients with forehead scars underwent surgical excision under local anesthesia and BTXA injection (50U/ml) after skin closure. Patients were evaluated preoperatively, at 6 and 12 months postoperatively (PO) for the evaluation of outcomes using the patient's self-assessment scar scale, the Patient and Observer Scar Assessment Scale (POSAS), and The Stony Brook Scar Evaluation Scale (SBSES). Patients' satisfaction was evaluated before and after PO using a 10-point visual analogue scale (VAS). Results: At 12-months PO, the aesthetic outcome was very satisfactory by 18 patients, satisfactory by 5 patients, and good by 3 patients, while 4 patients found the aesthetic outcome fair and poor with a significantly higher PO satisfaction score compared to the preoperative score. PO scores of the scar-assessment scales showed progressive improvements with significant differences in comparison to preoperative scores and between 6- and 12-months scores. The satisfaction score was negatively related to female gender and body mass index (BMI). Regression analysis defined a high pre-procedural patient's self-assessment scar scale and low SBSES scores as negative significant predictors of high satisfaction. Conclusion: BTXA injection after excision of disfiguring forehead scars provided highly satisfactory outcomes with a reduction of the scar width, irrespective of the scar shape.

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Section: Discussioncontrasting

confidence: 75%

Aesthetic Outcomes of Botulinum Toxin Injection for Management of Disfiguring Forehead Scars

Abdelmaksoud,

Rashwan,

Omran

2021

SJMS

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“…Autologous fat grafting (ie, lipotransfer) of adipose tissue‐derived stem cells (ADSCs) for patients with keloids has been shown to improve scar texture, pliability volume, and elasticity. This is achieved by the inhibition of fibroblast proliferation and ECM formation 54 …”

Section: Emerging Treatmentsmentioning

confidence: 99%

Update on management of keloid and hypertrophic scars: A systemic review

Elsaie

2021

J of Cosmetic Dermatology

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Numerous therapeutic strategies have been described for prevention and reduction of hypertrophic scars and keloids, but none of the treatments is effective in all patients. No universal consensus in treatment regimen has been established, and there is limited evidence‐based literature to guide the correct management. The process of scar development is complex and requires deeper understanding of the molecular mechanisms that cause their development and recurrences. Despite many available modes of targeting keloid and hypertrophic scars, yet they remain an ongoing challenge to patients and clinicians. To date, no one therapy has been universally accepted as the gold standard for the treatment of all excessive scars nor has the capability of complete scar resolution The search of literature included peer‐reviewed articles including clinical trials and scientific reviews. Literature was identified from electronic databases (MEDLINE/PubMed) through May 2021 and references of respective articles and only the articles published in English language were included.

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“…Contour deformities of the face requiring soft tissue augmentation are usually associated with hyperpigmentation of overlying skin (A. Bashir et al, 2020). These deformities often result from a variety of conditions like trauma, infections, and certain acquired diseases (Rao et al, 2020). Contour deformities of the face cause both functional as well as esthetic problems for the patients (Nigmatov et al, 2021).…”

Section: Introductionmentioning

confidence: 99%

“…Bashir et al, 2020). These deformities often result from a variety of conditions like trauma, infections, and certain acquired diseases (Rao et al, 2020). Contour deformities of the face cause both functional as well as esthetic problems for the patients (Nigmatov et al, 2021).…”

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confidence: 99%

Fat grafts enriched with ex‐vivo expanded adipose stem cells improve hyperpigmentation of face

Bashir

Afzaal

et al. 2023

Cell Biology International

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Facial contour deformities associated with pigmentary changes are of major concern for plastic surgeons being difficult to treat. No definite ideal treatment option is available to address simultaneously both the contour defects as well as related hyperpigmentation. The aim of the current study is to compare long-term effects of conventional adipose tissue grafting and ex-vivo expanded ASC-enriched adipose tissue grafting for the treatment of contour deformities related pigmentary changes on the face. In this study, 80 patients of contour deformities of face with hyperpigmentation were recruited after informed consent. Two techniques, that is, conventional fat grafting (C-FG) and fat grafts enriched with expanded adipose stem cells (FG-ASCs) were used to address the pigmentation. Both techniques were explained to patients and enrolled patients were divided into two groups, that is, C-FG and FG-ASCs as per patients' choice and satisfaction. Patients of the FG-ASCs group were treated with FG-ASCs while patients of C-FGs group were treated with C-FG (without expanded ASCs). Patients were followed for 12 months and improvement in face pigmentation was assessed clinically as well as measured objectively. Patients' satisfaction was also documented as highly satisfied, satisfied, and unsatisfied. This clinical trial was registered at www.clinicaltrials.gov with ID: NTC03564808. Mean age of patients was 24.42 (±4.49), 66 patients were females.Forehead was involved in 61.20% cases, cheek in 21.20% cases, chin in 11.20% cases, and nose in 6.20% cases. In GF-ASCs group, the integrated color density was decreased (1.08 × 10 6 ± 4.64 × 10 5 ) as compared with C-FG group (2.80 × 10 5 ± 1.69 × 10 5 ). Patients treated with fat grafts enriched with expanded ASCs were significantly more satisfied as compared with patients treated with C-FG only. In conclusion, ASC-enriched autologous fat grafting is preferred option for improving the contour deformities related increased pigmentation of face skin.

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A Study of Aesthetic and Functional Outcome Following Structural Fat Grafting for Facial Scars and Contour Deformity

Cited by 4 publications

References 11 publications

Aesthetic Outcomes of Botulinum Toxin Injection for Management of Disfiguring Forehead Scars

Aesthetic Outcomes of Botulinum Toxin Injection for Management of Disfiguring Forehead Scars

Update on management of keloid and hypertrophic scars: A systemic review

Fat grafts enriched with ex‐vivo expanded adipose stem cells improve hyperpigmentation of face

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