Though being highly stain-resistant and durable, recently, the harmful effects of fluorinated chemicals on the environment and organisms have gained people's attention. It has now become necessary to find non-fluorinated alternatives with comparable properties. Current research shows that non-fluorinated materials have achieved excellent hydrophobicity, but oleophobicity or stain-resistance is still difficult to reach. In this review, the chemistry of hydrophobic materials, morphology control of textiles, and the enhancement of durability of coatings are respectively discussed and summarized with examples. The combination of these techniques would help develop better repellency. This review also attempts to elucidate and discuss the necessity to consider textile properties according to end-use requirements, the asymmetric wettability design to increase comfort and the possible directions for future research on designing non-fluorinated durable stain-resistant textiles.