A Study of Central Corneal Thickness in Glaucoma and Nonglaucoma Patients in a West African Population

Abstract

There was no significant difference between mean CCT of cases and controls in the right eye (P = 0.08), but there was a weakly significant difference in the CCT of the left eye (P = 0.05). Also, there was no correlation between cup-to-disc ratio and CCT.

Central corneal thickness in newly diagnosed glaucoma patients in South West Ethiopia: a cross-sectional study

“…Similar findings have been reported from clinic-based studies among black glaucoma patients in Ethiopia (518.68 ± 32.92 μm) [17], Uganda (516.19 ± 39.95 μm); [18] and African Americans (518 μm) [19]. Among patients with glaucoma in West Africa, findings ranged from 524.28 μm to 536.91 μm [12, 20, 21]. …”

Central Corneal Thickness Measurement in Sub-Saharan Africa: Review

“…This thinner average of CCT was similar between populations living in SSA and African Americans and Afro-Caribbeans [43]. But despite of the most of these finding, there was one study led in the West African population, concluded that CCT may predict the development of glaucoma; however, it may not be a powerful predictor at the ranges of CCT [30].…”

“…CCT for non glaucomatous subjects 1637 non-glaucomatous patients drawn from 5 sub-Saharan countries (South Africa, Nigeria, Ghana, Cameroon, Ethiopia) were assessed after collection of the articles from Pubmed database, Google, Embase [9,10,23,24,25,26,27,28,29,30] The largest cluster of average CCT for non-glaucomatous African subjects was between 512.4 and 550 µm.…”

“…CCT=central corneal thickness; IOP= intraocular pressure; GAT= Goldmann aplanation tonometer; NCT= noncontact tonometer CCT for glaucomatous subjects 705 glaucomatous patients drawn from 5 sub-Saharan countries (Ghana, Uganda, Nigeria, Ethiopia, Ivory Coast) were assessed after collection of the articles from Pubmed database, Google, Embase [25,30,42,43,44]. Study characteristics are summarized in Table 2.…”

“…Some study did not bring out the relationship between age and CCT value [42]; some of them showed no significant difference between the mean age [30,44] and some of them have the same result as other studies, showed the CCT is thicker in younger age and thinner in older age [25,43]. According to the sex of the patients, one study did not bring out the relationship between gender of the patient and the CCT value [42]; no significant difference between the gender distribution founded for 2 studies [30,44] the CCT was thicker for male patient founded in 1 study [25] and it was slightly higher in female than in male for 1 study [43].…”