A Study of Clinical Features and Laboratory Profile of Dengue Fever in Outpatient Setting

Goweda, Reda; Faisal, Ahmed

doi:10.37268/mjphm/vol.20/no.2/art.422

Cited by 7 publications

(8 citation statements)

References 12 publications

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“…Fever (96.5%) was the most common clinical symptom in this study and was the common finding in other studies too (7,9,(11)(12)(13)(14)(15)(16)(17)(18)(19)(20). The second most common symptom was headache (40.6%) which was similar to the findings of other studies (7,13).…”

Section: Discussionsupporting

confidence: 90%

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Clinical and haematological profile of dengue among adult patients at a tertiary care hospital in Pokhara

Dhungana

Banstola

Banjara

2022

Preprint

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IntroductionDengue is an important infectious disease. This disease is prevalent in the terai belts of Nepal mainly. But in the last few years, the cases are in increasing trend in the hilly areas of Nepal also. Hence this study was done in an aim to study the clinical and haematological profile of the dengue cases.MethodsThis was a retrospective cross-sectional quantitative study done at a tertiary teaching hospital of Pokhara, Nepal after obtaining ethical approval from the institutional ethical committee. The data of serologically confirmed dengue cases, during the period of August 2019 to December 2019, of age above 15 years, were collected and analysed using SPSS 20. Descriptive analysis in terms of mean, median, percentage as well as t-test for nominal and chi-square tests were used to compare different parameters. P-value≤ 0.05 was considered statistically significant.ResultsOut of 922 patients, approximately one-half (50.5%) cases were seen during the month of September. Most (82.8%) were the inhabitants of Kaski district. Median age of presentation was 29 years with slightly more cases of males (52.4%). Three hundred and forty seven patients were admitted. Fever (96.5%) and headache (40.6%) were the most common symptoms on presentation of admitted cases. Leukopenia (55.3%) was more common than thrombocytopenia (47.6%) in the admitted cases. On comparison between admitted patients with warning signs and those without signs, no significant variation was seen in terms of age, total leukocyte count and total platelet count.ConclusionDengue is common in young population. Fever, headache and gastrointestinal symptoms are common among dengue patients. Leukopenia and thrombocytopenia are common laboratory features of dengue.

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Section: Discussionsupporting

confidence: 90%

“…With similar cut-off values also, the difference may be likely due to the timing of blood analysis also. Some may have been in febrile phase whereas others may have been in critical phase (12, 13, 18, 19, 22).…”

Section: Discussionmentioning

confidence: 99%

Clinical and haematological profile of dengue among adult patients at a tertiary care hospital in Pokhara

Dhungana

Banstola

Banjara

2022

Preprint

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“…This study also replicate this statement. Other study also had the similar findings 11,12 . This study also showed that decreasing platelet count is associated with the severe dengue.…”

Section: Discussionsupporting

confidence: 75%

“…On the other hand, prevalence of retro orbital pain was much lower than other studies (46% vs. 78%) 12 . Previous history of dengue is found to be the predictor of severity.…”

Section: Discussioncontrasting

confidence: 72%

The Predictors of the Severity of Dengue Fever: A Cross-Sectional Study in a Tertiary Care Center of Bangladesh

et al. 2021

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Background: Dengue is an endemic disease for Bangladesh with occasional outbreak. Little is known about the predictors of severe dengue. Methods: This cross sectional study was conducted in the medicine department of Dhaka Medical College from April 2019 to March 2020. Total 199 consecutive patients were enrolled in this study. For the purpose of the analysis, dengue fever was classified as group I and dengue hemorrhagic fever and dengue shock syndrome was classified as group II. Results: The mean (SD) age of the study population was 28.5(12.1) and 87.4% were less than 40 years of age. The male and female ratio was about 3:1. Among the total study population, 149(74.9%) patients had DF, 46 (23.1%) had DHF and only 4 (2%) had DSS on presentation. Baseline demography and clinical presentation did not significantly differ between classical dengue and severe dengue. Previous history of dengue had low association with severity (RR, 95%CI, phi, P value; 1.2, 1.04-1.40, 0.25, 0.001).Most of the laboratory parameters were similar between the groups. The number of platelet count was significantly lower in DHF and DSS [median (IQR) 43500(16500-95250], than DF [median (IQR) 65000(33000-1170000, p-value 0.01] Conclusion: Previous infection with dengue virus and decreasing platelet count are the predictors of the severe dengue. J Dhaka Medical College, Vol. 29, No.1, April, 2020, Page 77-82

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“…One study on the dengue fever prevalence assessed that 38 million people in 127 states are at jeopardy of contracting virus of dengue. According to several recent studies, around 3.6 billion people are at risk of getting dengue infections, with around 230 million new infections each year, including over two million cases of serious disease (DHF / DSS) and 21,000 expiries [9][10] . Dengue infection should be treated as a solitary ailment with various clinical pictures, vacillating from symptomless situations to severe clinical sequences, which may result in high mortality and morbidity.…”

Section: Introductionmentioning

confidence: 99%

A Retrospective Study on Laboratory Profile and Clinical Parameters of Dengue Fever Patients

Kumar¹,

Sarwari²,

Arain³

et al. 2021

PJMHS

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Introduction: Over the past decade, the number of cases of dengue fever has augmented intensely globally. Half the world's population is now under threat. Pakistan has also very high dengue fever per year, with regular reports of dengue outbreaks compared to other countries. Dengue infection should be treated as a solitary ailment with various clinical pictures, vacillating from symptomless situations to severe clinical sequences, which may result in high mortality and morbidity. Aim: To investigate the laboratory parameters and clinical profile in patients with dengue fever. Study Design: A Retrospective observational study. Place and Duration: In the Department of Medicine of Jalan Bani Bu Ali hospital Oman for one-year duration from July 2020 to July 2021. Methods: At least IgM positive or NS1 positive or IgM with NS1 positive or reactive ELISA assay for dengue fever detection but without any co-infection, bone marrow disease confirmed the cases of dengue without other confounding factors, such as alteration of clinical and laboratory data. The results were analyzed for the study. SPSS 21.0 was applied for Statistical analysis. Results: A total of 52 cases were tested positive for dengue fever. The patients mean age was 27.60 +/- 13.98 years and vacillated from 13 to 75 years. Of the total number of patients, 30 (57.69%) were in the age group 21 to 40 years. Of the 52 cases, 36 (69.23%) were male, 16 (30.77%) were female with M:F ratio was 2.2: 1. 42 (80.77%) of all cases were hospitalized for 5 days or less, and 10 (19.23%) were hospitalized for more than 5 days. The mean hospital stay was 3.67±1.40, ranging from 2 to 8 days. Fever was observed in all (100%) of the total number of cases. Conclusions: In this analysis, all patients have fever, and body pain, headache and malaise were communal signs, but a substantial quantity of cases also had respiratory and gastrointestinal symptoms such as nausea, abdominal pain, vomiting, dry cough and diarrhea. Keywords: Dengue fever, clinical profile, retrospective study, laboratory profile, thrombocytopenia

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A Study of Clinical Features and Laboratory Profile of Dengue Fever in Outpatient Setting

Cited by 7 publications

References 12 publications

Clinical and haematological profile of dengue among adult patients at a tertiary care hospital in Pokhara

Clinical and haematological profile of dengue among adult patients at a tertiary care hospital in Pokhara

The Predictors of the Severity of Dengue Fever: A Cross-Sectional Study in a Tertiary Care Center of Bangladesh

A Retrospective Study on Laboratory Profile and Clinical Parameters of Dengue Fever Patients

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