A Study of Effectiveness of Medical Therapy in Benign Prostatic Hyperplasia Patients in HUSM

Abstract

Introduction: Benign prostate hyperplasia (BPH), a progressive disease, can cause various urinary complications if left untreated. Aims and Objective: The current study was desigined to compare international prostate symptom score (IPSS), urine flow rate (Qmax), Prostate specific antigen (PSA) in pre and post treatment among patients with Benign prostate hyperplasia and to asses their quality of life. Methodology: A cross sectional study was designed at Hospital Universiti Sains Malaysia, including all patients diagnosed as BPH from year 2007 to 2010. Based on inclusion and exclusion criteria 307 subjects were selected. New set of International Prostate Symptom Score (IPSS) and urine flow rate (Qmax) was obtained from all selected patients. SPSS version 19 was used for statistical analysis. Result: Out of the 307 patients currently treated at Hospital University Sains Malaysia (HUSM), 268(87.3%) were Malays, 38(12.4%) were Chinese and 1(0.3%) was Indian. Majority of the patients having BPH were above 50 years of age. One hundred and seven (34.9%) patients were associated with hypertension, followed by diabetes mellitus 12 (3.9%). urine peak flow rate (Qmax) had mean difference of 11.74 and 14.41ml/ sec, which shows the medical therapy do improve urine flow rate and benign prostatic hyperplasia (p<0.001). The prostate size also showed an increase having mean difference from 36.12 to 38.14cc 3 (p<0.001). There is significant relation between prostate gland volume and serum prostatic specific antigen (p<0.001). Conclusion: Benign prostatic hyperplasia although a benign condition, but still interferes with the normal life style of the patients. By initiating medical treatment this disease can not only be treated but also significantly improves the quality of life of the patients.

Risk factors of hepatitis B virus surface antigen carriage and serological profile of HBsAg carriers in Lomé Togo, 2016

“…Of the infected persons, 13.3% were still infectious, and these were all women from the Kabyè-tem ethnic group. Our findings corroborate the results of a previous study that observed that the regions of highest HBsAg seroprevalence among 15–24 years old individuals were the central region (27.7%) and the Kara region (23.1%), which are inhabited by the Kabyè-tem [9]. This ethnic group is the second largest in Togo.…”

“…In the hospital-based Lomé study and the national survey among people aged 15 to 24 years there was a statistically significant difference in the prevalence of HBsAg between the two genders [9, 10]. This discrepancy may be due to our smaller sample size.…”

“…A previous study estimated the prevalence of this disease in Togo to be 16.4% among young people (aged 15–24 years) in 2010 [9] it varied significantly with gender, marital status, place and region of residence. In that study, the prevalence was 19.2% among males and 13.9% among females.…”