A study of lipid levels in Indian patients with coronary arterial disease

Krishnaswami, S; Prasad, Niraj K.; Jose, V

doi:10.1016/0167-5273(89)90013-2

Cited by 32 publications

(14 citation statements)

References 3 publications

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“…This study, which is similar to other studies carried out on expatriate Pakistani populations 21 and native populations in India 22 , showed an association of CAD with hypertension, diabetes and smoking. In particular, it showed the relevance of current heavy smoking, either in cases or their spouses, to CAD which is similar to data found in expatriate Bengalis 23 .…”

Section: Discussionsupporting

confidence: 91%

Waist-hip ratio and low HDL predict the risk of coronary artery disease in Pakistanis

Nishtar

Wierzbicki

Lumb

et al. 2004

Current Medical Research and Opinion

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Section: Discussionsupporting

confidence: 91%

Waist-hip ratio and low HDL predict the risk of coronary artery disease in Pakistanis

Nishtar

Wierzbicki

Lumb

et al. 2004

Current Medical Research and Opinion

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“…Thus, the lower level of total cholesterol in Asian Indians compared with Caucasians may be misleading if we fail to recognize that the mean levels of total cholesterol and triglycerides in Asian Indians with CAD are 2WO nig/dl lower than in Caucasians with CAD. ', 16,24 The HDL cholesterol levels are low and triglyceride levels are high in Asian Indian patients with CAD.24 Univariate analysis has shown that the relative risk of MI correlates directly with triglyceride levels and inversely with HDL cholesterol levels in both Caucasians and Asian Indians. In multivariate analysis, however, the ratio of total cholesterol to HDL (TCMDL ratio) emerges as the most powerful predictor of MI in both pop ulation groups, with triglyceride becoming an insignificant contributor.j4 The TCMDL ratio was found to be superior in predicting the risk of CAD in the Physicians Health Study, the Frainingham Heart Study, and in explaining the interpopulation differences in CAD mortality in 19 industrialized co~ntries.…”

Section: Conventional Risk Factors For Cad Among Asian Indiansmentioning

confidence: 99%

Malignant coronary artery disease in young asian indians: Thoughts on pathogenesis, prevention, and therapy

M.D.¹,

Mehta

1995

Clinical Cardiology

148

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Summary: Asian Indians have the highest rates of coronary artery disease (CAD) of any ethnic group studied, despite the fact that nearly half ofthis group are life-long vegetarians. CAD occurs early in age and generally follows a malignant course. Altho~igh the incidence of classic risk factors is low, high triglyceride and low high-density lipoprotein cholesterol levels, high lipoprotein(a) levels, hyperinsulinemia, and apple-type obesity all show a substantial prevalence in this population. Aggressive mtdification of life style beginning before adolescence seemsjustified in view ofthe malignant nature of CAD in this population. Pharmacologic intervention similar to that of secondary prevention of CAD seems justified as primary prevention in high-risk Asian Indians.

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“…1,2 India is experiencing a process of rapid epidemiological transition in terms of patterns of health and disease as communities transform their social and economic structures. [4][5][6] The people living in urban India have CVD rates similar to Indians living overseas, having the highest rates reported for Indian people. An increase in CVD mortality has been documented following the recent acculturation and socioeconomic development and the burden of disease is predicted to increase over the next 20 years.…”

Section: Introductionmentioning

confidence: 99%

“…An increase in CVD mortality has been documented following the recent acculturation and socioeconomic development and the burden of disease is predicted to increase over the next 20 years. [4][5][6] The people living in urban India have CVD rates similar to Indians living overseas, having the highest rates reported for Indian people. 7,8 The prevalence of CVD in rural areas is half that of urban India.…”

Section: Introductionmentioning

confidence: 99%

Influence of fish consumption on the distribution of serum cholesterol in lipoprotein fractions: comparative study among fish‐consuming and non‐fish‐consuming populations

Bulliyya

2002

Asia Pac J Clin Nutr

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The objective of this study was to investigate serum lipoprotein levels in order to assess cardiovascular disease (CVD) risk factors between fish-consuming populations and non-fish-consuming populations, as it has been speculated that fish intake reduces CVD risk. A representative sample of one thousand subjects (529 men and 471 women) were selected, with ages ranging from 20 to 70 years, from 40 villages belonging to fish-consuming (500) or non-fish-consuming (500) populations. Serum lipoprotein lipids such as total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C) were analysed biochemically using standard procedures. The ratios of TC: HDL-C and LDL-C: HDL-C were computed. Mean values of serum LDL-C and the ratios of LDL-C: HDL-C and TC: HDL-C were significantly lower and HDL-C levels were higher in fish-consumers than in non-fish-consumers. The concentrations of HDL-C decreased with increasing age, while the reverse was true for LDL-C and for the LDL-C: HDL-C and TC: HDL-C ratios. There were significant sex differences for certain age groups in both of the population groups. The 5th, 50th and 95th percentile cut-off values for these parameters were lower in fish-consumers than in non-fish-consumers. The prevalence of individuals at risk of CVD because of low HDL-C (<35 mg/dL), high LDL-C (>130 mg/dL) and their atherogenic ratios (LDL-C: HDL-C >3.5 and TC: HDL-C>4.5) was significantly greater in non-fish-consumers. This study highlights that the fish-consuming population had a lower atherogenic risk than the non-fish-consuming population. The intake of fish may have substantial implications for public health and health economy by decreasing the risk of CVD. However, more studies are warranted to better define the mechanisms of cardioprotection by dietary fish and fish oils.

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A study of lipid levels in Indian patients with coronary arterial disease

Cited by 32 publications

References 3 publications

Waist-hip ratio and low HDL predict the risk of coronary artery disease in Pakistanis

Waist-hip ratio and low HDL predict the risk of coronary artery disease in Pakistanis

Malignant coronary artery disease in young asian indians: Thoughts on pathogenesis, prevention, and therapy

Influence of fish consumption on the distribution of serum cholesterol in lipoprotein fractions: comparative study among fish‐consuming and non‐fish‐consuming populations

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