A study of medication-related problems in stroke patients: A need for pharmaceutical care

Kanagala, Viswa Srujani; Anusha, Annapareddy; Rao, Bhukya Srinivasa; Challa, Siva Reddy; Nalla, Krishna Sri; Gadde, Raja Sree

doi:10.4103/2279-042x.185750

Cited by 11 publications

(7 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Previous studies investigating the role of pharmacists in various hospital departments and adult and pediatric patients have shown that their care can decrease the rate of drug-related problems and improve patient outcomes. [25,26] However, other studies have found that while the incidence of drug-drug interactions or DRPs may decrease there was no obvious difference in clinical outcomes. [27,28] Optimizing pharmacotherapy in the form of drug selection and avoiding major drug-drug interactions may inhibit disease complications and shorten hospital stays.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Evaluation of the effect of pharmaceutical care during inpatient treatment in a department of neurology: A retrospective study

Xiao

et al. 2022

Medicine

View full text Add to dashboard Cite

Common drug-related problems during neurology inpatient treatment can affect expected health results. Some interventions need to be implemented to reduce DRPs. To explore the effect of care from clinical pharmacists during inpatient treatment. Inpatients treated in the department of neurology in the Second Hospital of Shanxi Medical University between January 1 to December 31, 2019, were retrospectively included. Those who received care from the clinical pharmacist service were assigned to the pharma-care group while the other patients were assigned to the control group. From the perspective of drugs, the two groups were compared in terms of types, antimicrobial use, and key monitoring of drug use. From the perspective of patients, the two groups were compared in terms of length of stay, hospital cost, drug cost and proportion. Propensity score matching was used to balance the baseline characteristics. A total of 2684 patients were included 554 in the pharma-care group and 2130 in the control group with a median of 9 days (range, 3–30 days) hospital stay. The groups showed no significant difference in age or gender. Length of stay, the proportion of drug cost, number of adverse events, cost of antibacterial agents, use of a single antibacterial agent, and use of three or more different antibacterial agents were similar between the groups. Medicine expenses cost more in the pharma-care group. The cost and types of intensive monitoring drugs were similar, but Defined Daily Doses were lower in the control group. While clinical pharmacists may play a positive role in the pharmaceutical care of inpatients, in this study the benefits were not obvious. This may be because of the small number of clinical pharmacists in the department of neurology with narrow coverage.

show abstract

Section: Discussionmentioning

confidence: 99%

“…Most studies to date have focused on the roles of pharmacists, such as the identification and classification of DRPs, [6,25,26] with intervention happening on the recommendations and acceptance of doctors. More direct measurement of the influence of clinical pharmacists is based on observations of the patient’s clinical outcomes.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the effect of pharmaceutical care during inpatient treatment in a department of neurology: A retrospective study

Xiao

et al. 2022

Medicine

View full text Add to dashboard Cite

show abstract

“…A study conducted in Northern Sweden looking into the occurrence and character of TRPs among old patients with dementia or cognitive impairment, found that ineffective drug/inappropriate drug (efficacy problem category) and unnecessary drug therapy were the most common TRPs among patients with an earlier stroke (Pfister et al, 2017). In India, 120/133 patients with stroke were found to have at least one TRPs, and drug efficacy problem was found to be the highest among the TRPs identified, accounting for 35.0% (Kanagala et al, 2016). In a study conducted in Germany, TRPs occurred in 105/155 (67.7%) patients with transient ischemic attack or ischemic stroke, giving a mean of 1.80 ± 2.00 TRPs per patient; inappropriate “drug” therapy, “indication”, and “dosage” were the most common TRPs identified (Hohmann et al, 2012).…”

Section: Discussionmentioning

confidence: 99%

Identifying treatment related problems and associated factors among hospitalized post-stroke patients through medication management review: A multi-center study

Basheti

Ayasrah

Ahmad

2019

Saudi Pharmaceutical Journal

View full text Add to dashboard Cite

BackgroundStroke is a major cause of disability and one of the leading causes of death among the elderly. Treatment related problems can lead to undesirable consequences. The Medication Management Review (MMR) service is aimed at identifying, resolving and preventing TRPs, subsiding the undesirable outcomes associated with TRPs.ObjectivesTo explore the types, frequencies and severity of TRPs amongst post-stroke patients recruited through hospitals via conducting the MMR service by clinical pharmacists in Jordan. Associations between patient factors and the identified TRPs were explored.MethodsThis cross-sectional descriptive study was conducted over three months in 2017 in different geographical areas throughout Jordan. Randomly recruited patients were interviewed at the hospitals to collect their demographic data and clinical characteristics. Types/frequencies/severity of TRPs for each stroke patient were identified by a clinical pharmacist. Associations between the identified TRPs and patient’s factors were explored through multiple regression analysis.Key findings:Out of 198 stroke patients (mean age: 56.6 ± 14.2) who completed the study, 110 (55.6%) were males. Many of the patients (82 (41.6%)) were smokers and 61 (69.2%) had hypertension and/or diabetes. The mean number of TRPs per patient was 2.5 ± 1.1. The most common TRP categories involved efficacy issues (198 (40.6%)), inappropriate drug adherence (136 (27.9%)) and inappropriate patient knowledge (114 (23.4%)). More than 70.0% (342/487) of the identified TRPs were of major severity. Higher number of TRPs was found to be associated with being a male, having a lower educational level, being a current smoker, having a higher number of drugs and a poorer quality of life.ConclusionLack of drug efficacy, inappropriate drug adherence and patient knowledge were the major TRPs identified via delivering the MMR service to post-stroke patients. The identified TRPs highlights the importance of the MMR service, and supports planning future strategies aimed at decreasing the incidence of strokes.

show abstract

“…A study conducted in Europe revealed that the use of medication as a preventive measure for stroke patients is ineffective to a significant extent, with a rate of 32.28%. 18 The primary concern in tertiary prevention for stroke patients extends beyond the efficacy of medications, encompassing the issue of patient adherence to medication, which hinders the attainment of ideal tertiary preventive outcomes. A multicenter study conducted in a hospital revealed that 70% of the patients who received pharmacological treatment exhibited an increase in severity following drug therapy.…”

Section: Methods Study Designmentioning

confidence: 99%

Prevention Program for People Living with Stroke in Low and Middle-Income Country: A Systematic Review

Lahdji,

Pudjonarko,

Shaluhiyah

2024

JPKI

View full text Add to dashboard Cite

Background: Non-communicable diseases (NCDs) are the primary factors responsible for mortality and impairment on a global scale. By 2030, it is estimated that non-communicable diseases will comprise 80% of the global population. According to the World Health Organization (WHO), the risk of stroke will grow by 50% for the entire global population by 2022. Currently, it is projected that 1 in 4 individuals will suffer from a strokeMethod: This review was reported using the “Preferred Reporting Items for Systematic Reviews and Meta-Analysis” guideline and written using the “Synthesis without Meta-Analysis” method. The included studies for this review followed several criteria, including randomized controlled trials (RCT), English and Bahasa articles, using population was people living with stroke, intervention was any prevention and disability limitation, and outcomes were prevention measurements (primary, secondary, and tertiary prevention).Results: The study yielded multiple efficacious and streamlined preventive interventions implemented for stroke patients. Emphasizing risk factors as the main strategy for preventing health issues, using pharmacological treatments such as polypill, aspirin, and vitamins as a supplementary measure under the guidance of medical physicians and cardiologists. In addition, tertiary preventive initiatives encompass more than just administering drug treatment; they also require adherence to pharmaceutical protocols

show abstract

A study of medication-related problems in stroke patients: A need for pharmaceutical care

Cited by 11 publications

References 9 publications

Evaluation of the effect of pharmaceutical care during inpatient treatment in a department of neurology: A retrospective study

Evaluation of the effect of pharmaceutical care during inpatient treatment in a department of neurology: A retrospective study

Identifying treatment related problems and associated factors among hospitalized post-stroke patients through medication management review: A multi-center study

Prevention Program for People Living with Stroke in Low and Middle-Income Country: A Systematic Review

Contact Info

Product

Resources

About