A study of monoamine oxidase activity in the liver and brain of some fish of the Volga basin

Yagodina, O. V.; Basova, I. N.; Khovanskikh, A. E.

doi:10.1134/s1607672906020037

Cited by 5 publications

(2 citation statements)

References 8 publications

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“…MAO inhibition represents reduced inactivation of monoaminergic neurotransmitters (Hussien et al, 2013). MAO inhibition has previously been investigated mostly in the brains of mammals, including humans, while MAO activity in fish remains poorly understood (Yagodina et al, 2006). For example, Hussien et al (2013) found that the pesticide cypermethrin might cause MAO inhibition in rat brains, while similar MAO inhibition was also reported in the brains of mice after lead exposure (Liu et al, 2013a,b).…”

Section: Mao Activitymentioning

confidence: 90%

Morphological alterations and acetylcholinesterase and monoamine oxidase inhibition in liver of zebrafish exposed to Aphanizomenon flos-aquae DC-1 aphantoxins

Zhang

et al. 2014

Aquatic Toxicology

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Section: Mao Activitymentioning

confidence: 90%

Morphological alterations and acetylcholinesterase and monoamine oxidase inhibition in liver of zebrafish exposed to Aphanizomenon flos-aquae DC-1 aphantoxins

Zhang

et al. 2014

Aquatic Toxicology

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“…The goal of the present work was the study of the substrate and inhibitor specificity of liver MAO of fish of the order sturgeons -the giant sturgeon Huso huso, the starred sturgeon Acipenser stellatus, the Persian sturgeon Acipenser persicus, and the Russian sturgeon Acipenser gueldenstaedtii. Our first results of determination of the liver monoamine oxidase activity of this fish species are presented in the work [10].…”

Section: Introductionmentioning

confidence: 99%

Comparative enzymologic study of catalytical properties of liver monoamine oxidases of sturgeon fish

Yagodina

Basova

2013

J Evol Biochem Phys

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We carried out the comparative study of the substrate and inhibitory specificity of liver monoamine oxidases (MAO) of the giant sturgeon Huso huso, the starred sturgeon Acipenser stellatus, the Persian sturgeon Acipenser persicus, and the Russian sturgeon Acipenser gueldenstaedtii. Results of the substrate-inhibitor analysis with use of inhibitors chlorgilin and deprenil, as well as five specific substrates indicate homogeneity of these enzymes. All studied MAO have the several orders higher sensitivity to chlorgilin than to deprenil, with essential interspecies differences being observed. There are determined kinetic parameters of enzymatic deamination (K M and V) of tyramine, serotonin, noradrenalin, benzylamine, β-phenylethylamine, and N-methylhistamine. All studied enzymes have been established to have the higher activity toward serotonin and noradrenalin-substrates of the MAO A form as compared with benzylamine, β-phenylethylamine, and N-methylhistamine-substrate of the mammalian MAO B form, the maximal activity being characteristic of the giant sturgeon. and by predominant oxidation of substrates [1]. MAO, like other membrane-bound enzymes, are difficult to be isolated in a poor state; therefore, the substrate and inhibitor analyses are extremely convenient way of study of catalytical properties of this enzyme. Among the majority of MAO, of particular importance is enzyme of fish organs and tissues owing to an expressed peculiarity of its substrate and inhibitor characteristics. Based on results of the substrate-inhibitor analysis, a suggestion is put forward about the presence in liver and brain of the fish paku Piaractus mesopotamicus Holmberg [2], goldfish Carassius auratus L. [3], and the sheatfish Parasilus asotus [4] of one MAO form similar with the MAO A form of terrestrial mammals, while in liver of carp Cyprinidae [5], the rainbow trout Salmo gairdneri [6], and the zebrafish Danio rerio [7]-about the presence

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Catalytic properties of monoamine oxidase from the lamprey Lampetra fluviatilis liver

Yagodina

Basova

Lapin

2006

Dokl Biochem Biophys

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A study of monoamine oxidase activity in the liver and brain of some fish of the Volga basin

Cited by 5 publications

References 8 publications

Morphological alterations and acetylcholinesterase and monoamine oxidase inhibition in liver of zebrafish exposed to Aphanizomenon flos-aquae DC-1 aphantoxins

Morphological alterations and acetylcholinesterase and monoamine oxidase inhibition in liver of zebrafish exposed to Aphanizomenon flos-aquae DC-1 aphantoxins

Comparative enzymologic study of catalytical properties of liver monoamine oxidases of sturgeon fish

Catalytic properties of monoamine oxidase from the lamprey Lampetra fluviatilis liver

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