Background: Because of the drop in oestrogen levels, postmenopausal women typically those who have not had a menstrual period for 12 months straight experience major physiological changes. Bone density, muscle mass, and fat distribution all may be impacted by these modifications. As a result, BMI increases and changes in body composition are common in postmenopausal women, and these factors can impact the musculoskeletal system, including the spine. Weight control, core strengthening exercises, and posture training are among possible therapies for postmenopausal women to lessen the negative consequences of elevated BMI on spine health. Aim: This study uses an inclinometer to study the effect of body mass index on lumbosacral angle in post-menopausal women. The lumbosacral angle is associated with several issues that Postmenopausal women face. Postmenopausal women have a high prevalence of musculoskeletal issues. Objective: The objective is to evaluate the effect of body mass index on lumbosacral angle in post- menopausal women using an inclinometer. Materials and Methods: A cross-sectional study in which 96 post-menopausal women (45- 55 years) were included as per inclusion criteria using the Consecutive sampling method. Data was collected by assessing BMI, and lumbosacral angle using an inclinometer and analysis was done by INSTAT software. Result: The study included a total of 96 participants. 48 individuals were in the 40-50 age range, while 48 participants were in the 50-55 age range. So, by calculating the average of both the groups. Overall study results point to a relationship between postmenopausal women’s lumbosacral angle and body mass index. Conclusion: According to this study there is an effect of body mass index on lumbosacral angle in post-menopausal women using an inclinometer. We also found that the study showed alternation in the lumbosacral angle among postmenopausal women.