A study of psycho-behavioral patterns in patients emerging from general anesthesia using sevoflurane, propofol and their combination in early, intermediate and late post-operative period: A randomized controlled trial

Abstract

Background:It has been contended the general anesthetic agents also may affect the psycho-social behavior of the patients, especially during the emergence from GA. This assumes much significance in day cases where, patients have to be roadworthy and mentally stable before discharge.Aims:We compared the psycho-behavioral effects of propofol, sevoflurane and their combination, while emerging from anesthesia.Settings and Design:The patients coming for short duration day care anesthesia were studied in a prospective randomized controlled comparison.Materials and Methods:The psycho-behavioral changes in early, intermediate and late recovery period were studied in 60 consenting patients undergoing Total Intra Venous Anesthesia (TIVA) using Propofol, Volatile Induction and Maintenance Anesthesia (VIMA) using Sevoflurane and the combination of these two agents.Statistical Analysis:Statistical Analysis of the data and application of various statistical tests was carried out with help of Statistical Package for Social Services (SPSS version 18). Data were compiled, analyzed and presented as frequency, proportions, mean and standard deviation. The tests of significance, like Chi-square test, percentages, independent sample t test, paired t test, and P value were used in the study.Results and Conclusions:Both the modalities of GA, viz; TIVA and VIMA, do produce significant psycho-behavioral changes in the patients after GA, though transiently. So it is imperative for the Clinicians to anticipate the entire aspect of Psycho-behavioral patterns before discharging the day cases from the Post anesthesia Care Unit (PACU).

Effect of Integrated Psychobehavioral Care on Emotional-Behavioral Responses, Cognitive Changes in Outpatients with Schizophrenia Followed Up: Based on a Prospective Randomized Controlled Study

“…In the process of giving patient care, patients and patients' families were empowered to recognize the disease and fully understand the importance of adhering to medication in compliance with medical advice for treatment [ 22 ]. The patient's family members, under the guidance of the medical staff, maintain a good relationship with the patient, actively communicate with the patient, and give the patient emotional support so that the patient feels the warmth of the family and enhances the confidence to overcome the disease [ 23 ]. Giving corresponding psychological guidance according to different patients' different psychological states can effectively improve their mental health problems such as anxiety, depression, terror, hostility, and interpersonal sensitivity.…”

Awake craniotomy for supratentorial tumors or epileptogenic lesions in pediatric patients: a 16-year retrospective cohort study

“…This is consistent with evidence that both intravenous and inhalational anesthesia may lead to agitation and emotional lability on awakening. 24 No patients were subsequently diagnosed with a psychological disorder or reported longstanding detrimental effects attributed to awake surgery. This finding agrees with the reports by Riquin et al of no postoperative diagnoses of anxiety or trauma-related disorders and a 2019 review that did not find postoperative psychological sequelae related to awake surgery.…”