A Study of Symptomatology and Histopathology in Uterine Fibromyomas

Khyade, Rajeshwari Laxman; More, Rakhi M.; Shedge, Rakesh

doi:10.4172/2327-4360.1000156

Cited by 2 publications

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“…Leiomyomas are the most frequent benign mesenchymal neoplasms of the female genital tract, with an incidence of 4–11% and reaching up to 40% during the fifth decade [ 1 ]. Over the years, several histopathological subtypes and secondary changes have been described, encompassing hyaline degeneration, hydropic degeneration, myxoid changes, and calcifications.…”

Section: Introductionmentioning

confidence: 99%

A Giant Leiomyoma with Massive Cystic Hydropic Degeneration Mimicking an Aggressive Neoplasm: A Challenging Case with a Literature Review

et al. 2021

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Patient: Female, 32-year-old Final Diagnosis: Leiomyoma with massive cystic hydropic degeneration Symptoms: Abdominal distension • abdominopelvic mass • pelvic pain • urinary frequency Medication: — Clinical Procedure: Surgery Specialty: Obstetrics and Gynecology • Pathology • Surgery Objective: Rare disease Background: Leiomyomas are the most frequent benign tumors of the uterus. They often exhibit degenerative changes (hyaline, myxoid, hemorrhagic, hydropic, and cystic), which lead to varying and sometimes challenging clinical, radiological, and histopathological features. We present this case to highlight the importance of recognizing these variants and their differential diagnosis since they resemble forms of uterine sarcomas with a potential for misdiagnosis. Case Report: A 32-year-old single woman presented with large pelviabdominal masses mimicking, clinically and radiologically, an aggressive uterine or ovarian tumor. The masses collectively measured 33×24×15 cm, and a definite intraoperative diagnosis could not be made. Resection showed a giant leiomyoma with massive cystic hydropic degeneration. The patient underwent myomectomies with transposition of the ovaries into the lateral abdominal wall. Although the surgery was complicated by a massive hemorrhage with an approximate blood loss of 6 liters requiring blood transfusion and bilateral internal iliac artery ligation, the patient was discharged home on the fourth day after surgery, with an uneventful 16-month follow-up. Conclusions: Few leiomyomas showing this marked degree of hydropic degeneration have been reported in the literature. The differential diagnosis includes uncommon variants of leiomyomas (eg, intravenous leiomyomatosis), as well as uterine sarcomas (eg, low-grade endometrial stromal sarcoma) and ovarian carcinomas. Therefore, appropriate evaluation of the clinicopathological features is vital to ensure appropriate management and not to erroneously diagnose a benign leiomyoma as a more aggressive type of tumor.

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Section: Introductionmentioning

confidence: 99%

A Giant Leiomyoma with Massive Cystic Hydropic Degeneration Mimicking an Aggressive Neoplasm: A Challenging Case with a Literature Review

et al. 2021

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A case of cystic uterine fibroid removed laparoscopically

Kanda,

Tezuka,

Mizoguchi

et al. 2024

JAPANESE JOURNAL OF JSGOE

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We report a case of laparoscopic removal of a cystic uterine fibroid in a 42-year-old woman (G３P３). Transvaginal ultrasonography revealed a giant cystic tumor in the pelvis. The ovaries were unremarkable bilaterally; therefore, we suspected a tubal or peritoneal tumor and performed laparoscopic surgery. Intraoperatively, we observed a large cystic tumor continuous with the anterior uterine wall, with normal bilateral adnexa. We performed cystectomy, and the patient was diagnosed with cystic leiomyoma and has shown no recurrence postoperatively. Cystic uterine fibroids are rare and may mimic uterine adnexal tumors. Laparoscopic surgery as a diagnostic treatment was considered to be useful from the viewpoint of curability and minimal invasiveness.

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A Study of Symptomatology and Histopathology in Uterine Fibromyomas

Cited by 2 publications

References 0 publications

A Giant Leiomyoma with Massive Cystic Hydropic Degeneration Mimicking an Aggressive Neoplasm: A Challenging Case with a Literature Review

A Giant Leiomyoma with Massive Cystic Hydropic Degeneration Mimicking an Aggressive Neoplasm: A Challenging Case with a Literature Review

A case of cystic uterine fibroid removed laparoscopically

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