1969
DOI: 10.1016/0002-9343(69)90220-4
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A study of the long-term effect of therapy in chronic obstructive pulmonary disease

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Cited by 32 publications
(1 citation statement)
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“…Measurements which would appear at least to be directly affected by the removal of sputum from the bronchial tree may in fact be insensitive to such change and one must now review indirect methods of approaching the problem. Lest this conclusion should sound too pessimistic one should recall that a clinical review 17 showed that neither standard treatment with bronchodilators nor antibiotics or physiotherapy appeared to alter the long‐term welfare of the bronchitic and Howard 25 has emphasized the apparently inexorable decline of lung function in bronchitics referred to chest clinics. It is again the background in which the evaluation of mucolytics must be seen in proper context.…”
Section: Direct Approachmentioning
confidence: 99%
“…Measurements which would appear at least to be directly affected by the removal of sputum from the bronchial tree may in fact be insensitive to such change and one must now review indirect methods of approaching the problem. Lest this conclusion should sound too pessimistic one should recall that a clinical review 17 showed that neither standard treatment with bronchodilators nor antibiotics or physiotherapy appeared to alter the long‐term welfare of the bronchitic and Howard 25 has emphasized the apparently inexorable decline of lung function in bronchitics referred to chest clinics. It is again the background in which the evaluation of mucolytics must be seen in proper context.…”
Section: Direct Approachmentioning
confidence: 99%