1953
DOI: 10.1136/thx.8.1.1
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A Study of the Origin and Development of Lung Cancer

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Cited by 108 publications
(25 citation statements)
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“…Evidence in favour of this is that sarcoidosis involves the mucosa of the larger bronchi (Turiaf et al, 1952;Kalbian, 1957), and Raeburn and Spencer (1953) have demonstrated that malignant change may arise in postinflammatory scar tissue.…”
Section: Discussionmentioning
confidence: 99%
“…Evidence in favour of this is that sarcoidosis involves the mucosa of the larger bronchi (Turiaf et al, 1952;Kalbian, 1957), and Raeburn and Spencer (1953) have demonstrated that malignant change may arise in postinflammatory scar tissue.…”
Section: Discussionmentioning
confidence: 99%
“…Our data are therefore similar to other studies, specifically that performed by Auerbach et al, [26] who found a lack of association between smoking and SC. A possible explanation is that atypical epithelial cells exist around some scars that later undergo unregulated proliferation with the development of metaplastic and then neoplastic cells, [40][41][42][43][44][45] which may occur irrespective of carcinogen exposure from smoking. There may be a genetic blueprint within a scar that gives it the ability to become neoplastic.…”
Section: Discussionmentioning
confidence: 99%
“…In chronic repair in various sites malignancy sometimes eventually appears, and this is also true in interstitial lung disease (Raeburn & Spencer 1953 …”
Section: Interstitial Lung Diseaselmentioning
confidence: 99%