A study of the relationship between ABO blood groups, secretor status and infection with Neisseria gonorrhoeae

During the past eight decades, a large number of studies have examined the possible relationship between blood type and infection. Many publications reflect uncritical attempts to mathematically link unstratified or random data. The interaction of pathogen and erythrocyte membrane may reflect antigenic similarity, adhesion through specific receptors, or modulation of antibody response. Anthropological surveys suggest that the geographic and racial distribution of human blood groups reflects susceptibility of populations with specific blood types to the plague, cholera, smallpox, malaria and other infectious diseases.

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The role of ABO blood groups and secretor status in host defences

Blackwell

1989

FEMS Microbiology Letters

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Epidemiological studies on the associations between ABO blood group antigens, secretor status and susceptibility to infectious agents are summarized. Evidence for association of non‐secretion with some autoimmune diseases for which infectious aetiologies have been proposed is also given. Several hypothesis are proposed to explain the host‐parasite interactions underlying the epidemiological observations, and evidence to support or refute them is presented.

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A study of the relationship between ABO blood groups, secretor status and infection with Neisseria gonorrhoeae

Cited by 4 publications

References 5 publications

Blood Group Antigens as Receptors for Pathogens

Blood Group Antigens as Receptors for Pathogens

Relationship between infectious diseases and human blood type

The role of ABO blood groups and secretor status in host defences

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