A study of the separation of proteins from multicomponent mixtures by a semi-batch foaming process

Foam Fractionation as a Means to Recover and Fractionate Bioactives

“…At the isoelectric point, maximum enrichment and recovery was seen [14], this is concordant with results seen by Schnepf and Gaden [11]. The mass transfer coefficient was found for different feed concentrations and it was observed that this value increases with increasing concentration [14].…”

“…In this investigation the feed concentration, bubble size, superficial gas velocity and feed pH were again tested to see how the enrichment ratio and recovery were affected. Again it was found that enrichment and recovery increased with lower feed concentrations, lower gas velocity and smaller bubbles [14]. At the isoelectric point, maximum enrichment and recovery was seen [14], this is concordant with results seen by Schnepf and Gaden [11].…”

“…Further data generated can also be used to improve the mathematical model and can be applied to other mathematical models found in literature to see if this fits trends found previously e.g. the mass transfer model found by Hossain and Saleh [14]. Modelling based on mass balances may also provide more accuracy in terms of predictive functions.…”

Optimization of protein recovery by foam separation using response surface methodology

“…They reported that bubble size is affected by solution and gas-liquid surface properties, such as solution pH, protein concentration, surface viscosity, surface tension, and some operational parameters, such as the superficial gas velocity and size of sparger. Saleh and Hossain (2001) determined the bubble size distribution in a foam fractionation column to identify the underlying mechanism and design for an improved foam fractionation process. Wong et al (2001) measured the bubble size in a continuous system to calculate the interfacial area and reported that the smaller bubbles, which were obtained with lower feed concentration, lower air velocities and pH close to the isoelectric point, gave better protein enrichment.…”

Foam fractionation in recovery of captopril

“…The application of foam fractionation to biological materials, such as proteins, enzyme etc., is very much attractive (8)(9)(10). Surfactants represent a striking problem in water resources.…”