A Study of the Temperature-Dependent Micellization of Pluronic F127

Bohorquez, Maria; Koch, Cody; Trygstad, Troy; Pandit, Nivedita K.

doi:10.1006/jcis.1999.6273

Cited by 278 publications

(216 citation statements)

References 17 publications

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“…It is worth mentioning that in the present study the obtained experimental value for (I 1 /I 3 ) L121 is close to those reported for other pluronics with a similar PPO chain length [33], but much higher than that of pure PPO, indicating that PPO chains in the aggregate could be somewhat hydrated.…”

Section: Fluorescence Measurementssupporting

confidence: 90%

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Erratum to: Solution behavior of aqueous mixtures of low and high molecular weight hydrophobic amphiphiles

et al. 2010

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Mixtures of a hydrophobic triblock copolymer (L121, PEO 5 PPO 68 PEO 5 ) and a hydrophobic anionic surfactant (AOT, Sodium bis(2-ethylhexyl)sulfosuccinate), each alone forming turbid vesicular solutions in water, aggregate to produce a thermodynamically stable, transparent and isotropic solution. Mixed AOT/L121 aggregates could be confirmed by fluorescence, surface tension, differential scanning calorimetry (DSC) and isothermal titration calorimetry (ITC). In an isotropic region, where mixed aggregates are formed, there is a synergistic interaction between monomers of AOT and L121 in the mixture. In addition, Small Angle Neutron Scattering (SANS) experiments provided evidence that mixed aggregates have the shape of either spheres (with a certain polydispersity) or very short ellipsoids (axial ratio below 2), confirming a transition from giant multilamellar vesicles to small aggregates upon mixing the two hydrophobic amphiphiles. Upon dilution, the morphology changes to disk-like. From an examination of the results of all the methods the peculiar behavior of the mixed AOT/L121 system is explained.The online version of the original article can be found at http://dx.doi.

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Section: Fluorescence Measurementssupporting

confidence: 90%

“…As can be seen in Fig. 4, the I e /I 3 curves show a maximum, a behaviour that has been reported previously [33]. At low concentrations, pyrene molecules are distributed in the bulk solution, and therefore, the I e /I 3 ratios are low.…”

Section: Fluorescence Measurementssupporting

confidence: 85%

Erratum to: Solution behavior of aqueous mixtures of low and high molecular weight hydrophobic amphiphiles

et al. 2010

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“…A reduce in I 1 /I 3 was observed reflecting the incorporation of the probe into micellar, non-polar environment [20]. This represents that the restricted polarity around the pyrene starts to decrease radically before micelles are observed [19].…”

Section: Pyrene Fluorescence Spectramentioning

confidence: 90%

“…Firstly we considered the pyrene monomer spectrum. The initial I 1 /I 3 ratio decreased with the increase in surfactant concentration due to a increasingly less polar microenvironment [19]. A reduce in I 1 /I 3 was observed reflecting the incorporation of the probe into micellar, non-polar environment [20].…”

Section: Pyrene Fluorescence Spectramentioning

confidence: 97%

Study of Local Anaesthetics. Part 203*. Micellization of Heptacainium Chloride Studied By Spectral Methods in Aqueous Solution

Gališinová¹

2013

J Bioequiv Availab

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The formation of micelles of the local anaesthetic heptacainium chloride (substance, XIX) in aqueous solution was investigated by the pyrene absorption and the pyrene I 1 /I 3 ratio methods, respectively by optical density (OD) method for surface curvature measurement. First, the absorption spectroscopy in UV/VIS region was based on studying changes in characteristic absorption spectrum of pyrene in presence of surfactant. The resultant plot of the sum of absorbances for the entire key pyrene maximum as a function of the total surfactant concentration showed, in the region of the critical micellar concentration, a usual sigmoidal increase. The fluorescence emission spectroscopy in UV/VIS region of spectrum by the probe pyrene, second procedure, was applied for determination of the cmc from the detections of the pyrene I 1 /I 3 ratio as a function of the surfactant concentration. The pyrene ratio data were fitted by the Boltzmann-type sigmoid of declining progress. The third (OD) method used required microliters of surfactant solutions and standard microplate absorbance measurements.

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“…In addition, although both polyethylene glycol and poloxamer can be dissolved in water and methylene chloride, poloxamer is known to be a surfactant or an amphiphilic structure showing temperaturedependent rheological properties in aqueous solution, since it has another hydrophobic poly(propylene oxide) block compared with polyethylene glycol. 16,17 Thus, one of the unique properties of the organic phase containing PLGA and poloxamer could be its water-trapping ability. Poloxamer is thought to be diffused to the outer water phase during emulsification at a slower rate after trapping water into the organic phase, which it does more efficiently than polyethylene glycol, because of its amphiphilic nature.…”

Section: Methodsmentioning

confidence: 99%

Polymeric Nano-half-shells prepared by Simple Solvent Evaporation Method

2009

Bulletin of the Korean Chemical Society

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A Study of the Temperature-Dependent Micellization of Pluronic F127

Cited by 278 publications

References 17 publications

Erratum to: Solution behavior of aqueous mixtures of low and high molecular weight hydrophobic amphiphiles

Erratum to: Solution behavior of aqueous mixtures of low and high molecular weight hydrophobic amphiphiles

Study of Local Anaesthetics. Part 203*. Micellization of Heptacainium Chloride Studied By Spectral Methods in Aqueous Solution

Polymeric Nano-half-shells prepared by Simple Solvent Evaporation Method

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