A study of the triterpenes ofEuphorbia jaxartica

Abstract

We have previously reported the isolation of carbohydrates, alcohols, and acids from E. lamprocarpa Benth. [1].In this paper we give the results of a study of the triterpene compounds from E. jaxartica I)rokh.The eomminuted raw material was extracted with chloroform. The chloroform was distilled off and the residue was dissolved in acetone. The aeetone-spluble fraction was treated with petroleum ether and chromatographed on alumina. Elution was then carried out successively with petroleum ether, benzene, acetone, and methanol. A mixture with an authentic sample of euphol gave no depression of the melting point and their IR spectra were identical.The second ethereal eluate and the acetone eluate yielded crystals with the composition C~lH~zO , mp 126-127 ° C, [oz]~ ±0% The substance formed anO-acetyl derivative with mp 126 ° C. The properties of this substance were identical with those of euphorbol, also isolated from spurge [4]. A mixture of the substance that we had obtained with euphorbol gave no depression of the melting point, and their IR spectra were identical.

Hexacosonate of euphorbol fromEuphorbia jaxartica

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We haw~ previously reported the isolation from the epigeal part of E. jaxartica Benth of the triterpene compounds euphol, euphorbol, and fl-sitosterol [1].We have now investigated the roots of E. iaxartica collected in the Syr'dar'ya region in the flowering stage of the plant. The comminuted roots were extracted with chloroform.

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“…We haw~ previously reported the isolation from the epigeal part of E. jaxartica Benth of the triterpene compounds euphol, euphorbol, and fl-sitosterol [1].…”