A study of waist circumference, waist-hip ratio as markers of type 2 diabetes mellitus and their correlation with family history of diabetes

Gokhale, Vijayashree S.; Jagdale, Nilesh; Batra, Tanvi; Gulati, Shipra

doi:10.18203/2320-6012.ijrms20164425

Cited by 6 publications

(6 citation statements)

References 9 publications

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“…The matched results were found by some other investigators as well. [9][10][11][12][13][14][15] We found a decrease in TBIC, Hb and UBIC whereas an increase was noticed in % saturation, HbA1c, serum iron and fasting blood glucose levels. Our results were consistent with the work done and results found by some other researchers.…”

Section: Discussionmentioning

confidence: 99%

Biochemical assessment of iron profile in type 2 diabetes patients.

Shah

Rehman

Khan

et al. 2020

TPMJ

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Objectives: Iron profile is considered to be an important guide for improved health around the globe. An altered iron profile is a risk factor for numerous diseases. Extreme iron accretion in body results in damaging many cellular structures as well as in oxidative damage with many complications. Thus, iron profile must be considered in many ailments including DM. Study Design: Descriptive study. Setting: Department of Biochemistry, BMC Bannu and Department of Medicine, KGN Teaching Hospital Bannu-KPK. Period: January 2019 to June 2019. Material & Methods: 140 subjects were taken in this study, out of which 70 were suffering from type 2 diabetes and 70 were normal healthy controls. BMI was calculated by dividing body weight (Kg) to square of height (meters). The waist / hip circumference ratio was calculated by dividing the waist circumference (cm) to hip circumference (cm). Sphygmomanometer was used for blood pressure measurement. The serum iron, TIBC, UIBC, plasma glucose and HbA1c were measured by semi-auto analyzer. The serum ferritin was estimated by chemiluminescence method. The % transferrin saturation was calculated by formula serum iron (μg/dl) x 100/ TIBC (μg/dl). Result: The anthropometric parameters like weight, BMI, waist circumference, hip circumference, waist hip circumference ratio, systolic and diastolic blood pressure was statistically extremely significantly (p<0.001) increased in type 2 diabetes mellitus subjects as compared to healthy control subjects. The plasma fasting glucose, HbA1C, serum iron, % saturation and serum ferritin were statistically extremely significantly (p<0.001) increased and UIBC was statistically extremely significantly (p<0.001) decreased while TIBC and hemoglobin were statistically significantly (p<0.05) decreased in type 2 diabetes mellitus subjects as compared to healthy control subjects. Conclusion: Elevated iron and ferritin is a risk factor for diabetes and produce many complications. Proper management must be taken to remove the excess iron that can be very harmful to the body.”

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Section: Discussionmentioning

confidence: 99%

Biochemical assessment of iron profile in type 2 diabetes patients.

Shah

Rehman

Khan

et al. 2020

TPMJ

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“…We purposively selected Mangu Local Government Area in the central part of Plateau State, North-Central Nigeria for the study given our experience with the locality in previous studies (21,22). The area is home to persons of diverse ethnic affiliation though predominantly consisting of the Mwaghavul, Pyem, and Fulani.…”

Section: Study Areamentioning

confidence: 99%

Cardiovascular Anthropometry: What Is Best Suited for Large-Scale Population Screening in Sub-Saharan Africa?

Agbo

Zoakah

Isichei

et al. 2020

Front. Cardiovasc. Med.

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Background : Body mass index (BMI) measures overweight/obesity. It, however, especially in sub-Saharan Africa (SSA), misclassifies cardiometabolic risk. Central obesity measures are superior. We therefore sought to compare BMI, waist-to-hip ratio (WHR) and abdominal height (AH) in predicting cardiovascular disease risk in sub-Saharan Africa.Methods : Subjects had blood pressures, BMI, and WHR determined. Blood pressure was taken, weight and height measured to generate BMI, and AH measured with a new locally fabricated abdominometer. The ability of the anthropometric indices in identifying abnormal individuals needing intervention was assessed with sensitivity, specificity, and area under the receiver operator characteristic curve.Results : Adults totaling 1,508 (728 M/780 F) adults were studied. For BMI, 985 (65.3%) were normal, while 375 (24.9%), consisting of 233 males and 142 females, had normal WHR. Blood pressure was normal in 525 (34.8%) and 317 (21.0%) for systolic and diastolic blood pressures, respectively. Using BMI as gold standard, sensitivity, specificity, positive, and negative predictive values for WHR in males were 80.7, 37.5, 62.5, and 19.3%, respectively. For females and in the same order, they were 62.0, 34.3, 65.7, and 38.0%. For AH, it was equal in both genders at 82.6, 39.2, 60.8, and 17.4%. By receiver operating curves comparing AH, WHR, and BMI against blood pressure detection, the area under the curve was 0.745, 0.604, and 0.554 for AH, BMI, and WHR, respectively.Conclusion : Abdominometer-derived AH has a better sensitivity and greater area under the receiver operator curve compared with BMI and WHR in this sub-Sahara African population; implying superiority as a cardiovascular anthropometric index.

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“…Individually it is a risk factor, though not the only one and absence of Family history does not guarantee freedom from developing diabetes. 5 Aim of the present study is to estimate waisthip ratio, waist circumference in the study population and their relationship with type 2 diabetic patients with respect to gender.…”

Section: Introductionmentioning

confidence: 99%

A study of waist circumference and waist-hip ratio as markers of type 2 diabetes mellitus in an urban population of district Bareilly

Khan

Aḥmad

Saxena

et al. 2019

Int J Community Med Public Health

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Background: Type 2 diabetes mellitus belongs to a group of diseases labelled as lifestyle diseases and is on the rise in Asians especially Indians. Hence finding bio-markers is important to warn people and create awareness. Aim of the present study is to estimate waist-hip ratio, waist circumference in type 2 diabetic patients with respect to gender. Methods: A cross-sectional, community based study was conducted from February 2014 to February 2015 among adults in the age group of 30 year and above residing in area covered under UHTC of Bareilly City. A simple random sampling technique was adopted to achieve the desired sample size. 640 is the sample size came out to be by applying 3.8 4𝑃𝑄/d2 formula. Subject’s waist circumference, waist-hip ratio was measured in study samples. House to house survey was done for collecting data. Data tabulated and subjected to statistical analysis. Results: Prevalence of DM and IFG was more in those who were having high waist circumference and the association was also found to be statistically significant. The association was also found statistically significant between male high waist hip ratio and Diabetes Mellitus but no association was seen between female’s high waist-hip ratio and Diabetes Mellitus.Conclusions: High waist circumference can be a screening procedure for DM individuals in both sexes, but the same scenario we haven’t seen in high waist hip ratio among females and prevalence of DM. Appropriate waist circumference and waist-to-hip ratio values are complex because they are likely influenced by gender and other factors.

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A study of waist circumference, waist-hip ratio as markers of type 2 diabetes mellitus and their correlation with family history of diabetes

Cited by 6 publications

References 9 publications

Biochemical assessment of iron profile in type 2 diabetes patients.

Biochemical assessment of iron profile in type 2 diabetes patients.

Cardiovascular Anthropometry: What Is Best Suited for Large-Scale Population Screening in Sub-Saharan Africa?

A study of waist circumference and waist-hip ratio as markers of type 2 diabetes mellitus in an urban population of district Bareilly

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